HCPCS Level II · Transportation, medical and surgical supplies
A4221Supplies for maintenance of non-insulin drug infusion catheter, per week (list drugs separately)
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Source: CMS HCPCS quarterly update, October 2026. Page updated September 29, 2026.
About A4221
A4221 is an HCPCS Level II code in the A series (transportation, medical and surgical supplies), describing supplies for maintenance of non-insulin drug infusion catheter, per week (list drugs separately).
It was added to HCPCS effective 01/01/1997, and its current record took effect 01/01/2017.
Its Medicare coverage code is "C", meaning coverage is left to the Medicare contractor's judgment.
Details
- Short description
- Supp non-insulin inf cath/wk
- Date added
- 01/01/1997
- Action effective
- 01/01/2017
- BETOS
- D1E
Related A42xx codes
- A4206Syringe with needle, sterile, 1 cc or less, each
- A4207Syringe with needle, sterile 2 cc, each
- A4208Syringe with needle, sterile 3 cc, each
- A4209Syringe with needle, sterile 5 cc or greater, each
- A4210Needle-free injection device, each
- A4211Supplies for self-administered injections
- A4212Non-coring needle or stylet with or without catheter
- A4213Syringe, sterile, 20 cc or greater, each
- A4215Needle, sterile, any size, each
- A4216Sterile water, saline and/or dextrose, diluent/flush, 10 ml
- A4217Sterile water/saline, 500 ml
- A4218Sterile saline or water, metered dose dispenser, 10 ml
Common questions about A4221
Is HCPCS A4221 still valid?
- Yes. A4221 is active in the CMS October 2026 HCPCS file.
Does Medicare cover A4221?
- Its coverage code is "C": coverage is left to the Medicare contractor's judgment. Check the local coverage determination for your region.