HCPCS Level II · Procedures and professional services (temporary)
G0659Drug test(s), definitive, utilizing drug identification methods able to identify individual drugs and distinguish between structural isomers (but not necessarily stereoisomers), including but not limited to gc/ms (any type, single or tandem) and lc/ms (any type, single or tandem), excluding immunoassays (e.g., ia, eia, elisa, emit, fpia) and enzymatic methods (e.g., alcohol dehydrogenase), performed without method or drug-specific calibration, without matrix-matched quality control material, or without use of stable isotope or other universally recognized internal standard(s) for each drug, drug metabolite or drug class per specimen; qualitative or quantitative, all sources, includes specimen validity testing, per day, any number of drug classes
Source: CMS HCPCS quarterly update, October 2026. Page updated September 29, 2026.
About G0659
G0659 is an HCPCS Level II code in the G series (procedures and professional services (temporary)), describing drug test(s), definitive, utilizing drug identification methods able to identify individual drugs and distinguish between structural isomers (but not necessarily stereoisomers), including but not limited to gc/ms (any type, single or tandem) and lc/ms (any type, single or tandem), excluding immunoassays (e.g., ia, eia, elisa, emit, fpia) and enzymatic methods (e.g., alcohol dehydrogenase), performed without method or drug-specific calibration, without matrix-matched quality control material, or without use of stable isotope or other universally recognized internal standard(s) for each drug, drug metabolite or drug class per specimen; qualitative or quantitative, all sources, includes specimen validity testing, per day, any number of drug classes.
It was added to HCPCS effective 01/01/2017.
Its Medicare coverage code is "C", meaning coverage is left to the Medicare contractor's judgment.
Details
- Short description
- Drug test def simple all cl
- Date added
- 01/01/2017
- Action effective
- 01/01/2017
- BETOS
- T1H
Related G06xx codes
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- G0664Team remote e/m new pt 60mins
- G0665Team remote e/m est. pt 10mins
- G0666Team remote e/m est. pt 15mins
- G0667Team remote e/m est. pt 25mins
- G0668Team remote e/m est. pt 40mins
- G0669Outcome-aligned payment (oap) for technology-enabled chronic care management of early cardio-kidney-metabolic (eckm) conditions (hypertension, or two or more of: dyslipidemia, obesity/overweight with central obesity marker, prediabetes); initial 12-month period; per month
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Common questions about G0659
Is HCPCS G0659 still valid?
- Yes. G0659 is active in the CMS October 2026 HCPCS file.
Does Medicare cover G0659?
- Its coverage code is "C": coverage is left to the Medicare contractor's judgment. Check the local coverage determination for your region.