HCPCS Level II · Procedures and professional services (temporary)
G2216Take-home supply of injectable naloxone (provision of the services by a medicare-enrolled opioid treatment program); list separately in addition to code for primary procedure
✓ Active
Source: CMS HCPCS quarterly update, October 2026. Page updated September 29, 2026.
About G2216
G2216 is an HCPCS Level II code in the G series (procedures and professional services (temporary)), describing take-home supply of injectable naloxone (provision of the services by a medicare-enrolled opioid treatment program); list separately in addition to code for primary procedure.
It was added to HCPCS effective 01/01/2021.
Its Medicare coverage code is "C", meaning coverage is left to the Medicare contractor's judgment.
Details
- Short description
- Home supply inject naloxon
- Date added
- 01/01/2021
- Action effective
- 01/01/2021
- BETOS
- Z2
Related G22xx codes
- G2200Patient identified as an unhealthy alcohol user received brief counseling
- G2202Patient did not receive brief counseling if identified as an unhealthy alcohol user
- G2204Patients between 45 and 85 years of age who received a screening colonoscopy during the performance period
- G2205Patients with pregnancy during adjuvant treatment course
- G2206Patient received adjuvant treatment course including both chemotherapy and her2-targeted therapy
- G2207Reason for not administering adjuvant treatment course including both chemotherapy and her2-targeted therapy (e.g. poor performance status (ecog 3-4; karnofsky <=50), cardiac contraindications, insufficient renal function, insufficient hepatic function, other active or secondary cancer diagnoses, other medical contraindications, patients who died during initial treatment course or transferred during or after initial treatment course)
- G2208Patient did not receive adjuvant treatment course including both chemotherapy and her2-targeted therapy
- G2209Patient refused to participate
- G2210Residual score for the neck impairment not measured because the patient did not complete the neck fs prom at initial evaluation and/or near discharge, reason not given
- G2211Visit complexity inherent to evaluation and management associated with medical care services that serve as the continuing focal point for all needed health care services and/or with medical care services that are part of ongoing care related to a patient's single, serious condition or a complex condition. (add-on code, list separately in addition to home or residence or office/outpatient evaluation and management service, new or established)
- G2212Prolonged office or other outpatient evaluation and management service(s) beyond the maximum required time of the primary procedure which has been selected using total time on the date of the primary service; each additional 15 minutes by the physician or qualified healthcare professional, with or without direct patient contact (list separately in addition to cpt codes 99205, 99215, 99483 for office or other outpatient evaluation and management services) (do not report g2212 on the same date of service as 99358, 99359, 99415, 99416). (do not report g2212 for any time unit less than 15 minutes)
- G2213Initiation of medication for the treatment of opioid use disorder in the emergency department setting, including assessment, referral to ongoing care, and arranging access to supportive services (list separately in addition to code for primary procedure)
Common questions about G2216
Is HCPCS G2216 still valid?
- Yes. G2216 is active in the CMS October 2026 HCPCS file.
Does Medicare cover G2216?
- Its coverage code is "C": coverage is left to the Medicare contractor's judgment. Check the local coverage determination for your region.