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HCPCS Level II · Drugs administered other than oral method

J2251Injection, midazolam in 0.9% sodium chloride, intravenous, not therapeutically equivalent to j2250, 1 mg

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Source: CMS HCPCS quarterly update, October 2026. Page updated September 29, 2026.

About J2251

J2251 is an HCPCS Level II code in the J series (drugs administered other than oral method), describing injection, midazolam in 0.9% sodium chloride, intravenous, not therapeutically equivalent to j2250, 1 mg.

It was added to HCPCS effective 01/01/2023, and its current record took effect 10/01/2024.

Its Medicare coverage code is "D", meaning special Medicare coverage instructions apply.

Details

Short description
Inj midazolam in 0.9% nacl
Date added
01/01/2023
Action effective
10/01/2024
BETOS
O1E

Related J22xx codes

Common questions about J2251

Is HCPCS J2251 still valid?

Yes. J2251 is active in the CMS October 2026 HCPCS file.

Does Medicare cover J2251?

Its coverage code is "D": special Medicare coverage instructions apply. Check the local coverage determination for your region.