HCPCS Level II · Temporary national codes (non-Medicare)
S5521Home infusion therapy, all supplies (including catheter) necessary for a midline catheter insertion
✓ Active
Source: CMS HCPCS quarterly update, October 2026. Page updated September 29, 2026.
About S5521
S5521 is an HCPCS Level II code in the S series (temporary national codes (non-Medicare)), describing home infusion therapy, all supplies (including catheter) necessary for a midline catheter insertion.
It was added to HCPCS effective 01/01/2002.
Its Medicare coverage code is "I", meaning it is not payable by Medicare (another code or method is used).
Details
- Short description
- Hit midline cath insert kit
- Date added
- 01/01/2002
- Action effective
- 01/01/2002
- BETOS
- Z2
Related S55xx codes
- S5501Home infusion therapy, catheter care / maintenance, complex (more than one lumen), includes administrative services, professional pharmacy services, care coordination, and all necessary supplies and equipment (drugs and nursing visits coded separately), per diem
- S5502Home infusion therapy, catheter care / maintenance, implanted access device, includes administrative services, professional pharmacy services, care coordination and all necessary supplies and equipment, (drugs and nursing visits coded separately), per diem (use this code for interim maintenance of vascular access not currently in use)
- S5517Home infusion therapy, all supplies necessary for restoration of catheter patency or declotting
- S5518Home infusion therapy, all supplies necessary for catheter repair
- S5520Home infusion therapy, all supplies (including catheter) necessary for a peripherally inserted central venous catheter (picc) line insertion
- S5522Home infusion therapy, insertion of peripherally inserted central venous catheter (picc), nursing services only (no supplies or catheter included)
- S5523Home infusion therapy, insertion of midline venous catheter, nursing services only (no supplies or catheter included)
- S5550Insulin, rapid onset, 5 units
- S5551Insulin, most rapid onset (lispro or aspart); 5 units
- S5552Insulin, intermediate acting (nph or lente); 5 units
- S5553Insulin, long acting; 5 units
- S5560Insulin delivery device, reusable pen; 1.5 ml size
Common questions about S5521
Is HCPCS S5521 still valid?
- Yes. S5521 is active in the CMS October 2026 HCPCS file.
Does Medicare cover S5521?
- Its coverage code is "I": it is not payable by Medicare (another code or method is used). Check the local coverage determination for your region.