ICD-10-CM 2027
ICD-10 code for acidosis
From the official ICD-10-CM alphabetic index entry “Acidosis (lactic)”. Page updated September 29, 2026.
About coding acidosis
The ICD-10-CM code for acidosis is E87.20 (Acidosis, unspecified). The official index lists 21 more specific codes, so check the documentation for details such as type, cause, site or severity before settling on E87.20.
Within E87.2, choose E87.20 (unspecified) only when documentation doesn't support a more specific option: acute metabolic acidosis (E87.21), chronic metabolic acidosis (E87.22) and other acidosis (E87.29).
As a secondary diagnosis it is a CC (complication or comorbidity), which can move an inpatient stay into the "with CC" MS-DRG of its family, unless the principal diagnosis excludes it.
In MS-DRG v44.0, it is part of the grouping logic for DRG 640 (Miscellaneous Disorders of Nutrition, Metabolism, Fluids and Electrolytes with MCC, relative weight 1.3395), DRG 641 (Miscellaneous Disorders of Nutrition, Metabolism, Fluids and Electrolytes without MCC, relative weight 0.7865), DRG 791 (Prematurity with Major Problems, relative weight 4.1075) and DRG 793 (Full Term Neonate with Major Problems, relative weight 4.2195), in MDC 10 (Endocrine, Nutritional and Metabolic Diseases and Disorders) and MDC 15 (Newborns and Other Neonates with Conditions Originating in the Perinatal Period), as a principal or secondary diagnosis. The DRG a claim lands in depends on the principal diagnosis, procedures and any CC/MCC secondary diagnoses.
More specific acidosis codes (official index)
- in Type 1 diabetes E10.10 — Type 1 diabetes mellitus with ketoacidosis without coma
- with coma E10.11 — Type 1 diabetes mellitus with ketoacidosis with coma
- kidney, tubular N25.89 — Other disorders resulting from impaired renal tubular function
- lactic E87.20 — Acidosis, unspecified
- acute E87.21 — Acute metabolic acidosis
- chronic E87.22 — Chronic metabolic acidosis
- metabolic NEC E87.20 — Acidosis, unspecified
- with respiratory acidosis E87.4 — Mixed disorder of acid-base balance
- acute E87.21 — Acute metabolic acidosis
- chronic E87.22 — Chronic metabolic acidosis
- hyperchloremic, of newborn P74.421 — Hyperchloremia of newborn
- late, of newborn P74.0 — Late metabolic acidosis of newborn
- mixed metabolic and respiratory, newborn P84 — Other problems with newborn
- newborn P84 — Other problems with newborn
- renal (hyperchloremic) (tubular) N25.89 — Other disorders resulting from impaired renal tubular function
- respiratory E87.29 — Other acidosis
- acute J96.02 — Acute respiratory failure with hypercapnia
- chronic J96.12 — Chronic respiratory failure with hypercapnia
- complicated by
- metabolic
- acidosis E87.4 — Mixed disorder of acid-base balance
- alkalosis E87.4 — Mixed disorder of acid-base balance
- specified NEC E87.29 — Other acidosis
Common questions about acidosis ICD-10 codes
What is the ICD-10 code for acidosis?
- E87.20 — Acidosis, unspecified. More specific codes apply when the documentation supports them: E10.10, E10.11, N25.89, E87.20 and others below.
What is the ICD-10 code for lactic acidosis?
- E87.20 — Acidosis, unspecified.
What is the ICD-10 code for metabolic nec acidosis?
- E87.20 — Acidosis, unspecified.
What is the ICD-10 code for newborn acidosis?
- P84 — Other problems with newborn.
What is the ICD-10 code for renal acidosis?
- N25.89 — Other disorders resulting from impaired renal tubular function.
What is the ICD-10 code for respiratory acidosis?
- E87.29 — Other acidosis.
Is E87.20 billable?
- Yes. E87.20 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).
Can E87.20 be used as a principal diagnosis?
- Yes. The Medicare Code Editor doesn't restrict E87.20 as a principal diagnosis.
Is E87.20 a CC or MCC?
- E87.20 is a CC (complication or comorbidity) under MS-DRG v44.0, unless excluded by the principal diagnosis.