ICD-10-CM 2027
ICD-10 code for aplastic anemia
From the official ICD-10-CM alphabetic index entry “Anemia (essential) (general) (hemoglobin deficiency) (infantile) (primary) (profound) › aplastic”. Page updated September 29, 2026.
About coding aplastic anemia
The ICD-10-CM code for aplastic anemia is D61.9 (Aplastic anemia, unspecified). The official index lists 14 more specific codes, so check the documentation for details such as type, cause, site or severity before settling on D61.9.
Within D61, choose D61.9 (Aplastic anemia, unspecified) only when documentation doesn't support a more specific option: constitutional aplastic anemia (D61.0), drug-induced aplastic anemia (D61.1), aplastic anemia due to other external agents (D61.2), idiopathic aplastic anemia (D61.3) and other specified aplastic anemias and other bone marrow failure syndromes (D61.8).
As a secondary diagnosis it is a CC (complication or comorbidity), which can move an inpatient stay into the "with CC" MS-DRG of its family, unless the principal diagnosis excludes it.
In MS-DRG v44.0, it is part of the grouping logic for DRG 808 (Major Hematological and Immunological Diagnoses Except Sickle Cell Crisis and Coagulation Disorders with MCC, relative weight 2.1705), DRG 809 (Major Hematological and Immunological Diagnoses Except Sickle Cell Crisis and Coagulation Disorders with CC, relative weight 1.2262) and DRG 810 (Major Hematological and Immunological Diagnoses Except Sickle Cell Crisis and Coagulation Disorders without CC/MCC, relative weight 1.075), in MDC 16 (Diseases and Disorders of the Blood and Blood Forming Organs and Immunological Disorders), as a principal or secondary diagnosis. The DRG a claim lands in depends on the principal diagnosis, procedures and any CC/MCC secondary diagnoses.
More specific aplastic anemia codes (official index)
- congenital D61.09 — Other constitutional aplastic anemia
- drug-induced D61.1 — Drug-induced aplastic anemia
- due to
- drugs D61.1 — Drug-induced aplastic anemia
- external agents NEC D61.2 — Aplastic anemia due to other external agents
- infection D61.2 — Aplastic anemia due to other external agents
- radiation D61.2 — Aplastic anemia due to other external agents
- idiopathic D61.3 — Idiopathic aplastic anemia
- red cell (pure) D60.9 — Acquired pure red cell aplasia, unspecified
- chronic D60.0 — Chronic acquired pure red cell aplasia
- congenital D61.01 — Constitutional (pure) red blood cell aplasia
- specified type NEC D60.8 — Other acquired pure red cell aplasias
- transient D60.1 — Transient acquired pure red cell aplasia
- specified type NEC D61.89 — Other specified aplastic anemias and other bone marrow failure syndromes
- toxic D61.2 — Aplastic anemia due to other external agents
Common questions about aplastic anemia ICD-10 codes
What is the ICD-10 code for aplastic anemia?
- D61.9 — Aplastic anemia, unspecified. More specific codes apply when the documentation supports them: D61.09, D61.1, D61.1, D61.2 and others below.
What is the ICD-10 code for congenital aplastic anemia?
- D61.09 — Other constitutional aplastic anemia.
What is the ICD-10 code for drug-induced aplastic anemia?
- D61.1 — Drug-induced aplastic anemia.
What is the ICD-10 code for idiopathic aplastic anemia?
- D61.3 — Idiopathic aplastic anemia.
What is the ICD-10 code for red cell aplastic anemia?
- D60.9 — Acquired pure red cell aplasia, unspecified.
What is the ICD-10 code for toxic aplastic anemia?
- D61.2 — Aplastic anemia due to other external agents.
Is D61.9 billable?
- Yes. D61.9 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).
Can D61.9 be used as a principal diagnosis?
- Yes. The Medicare Code Editor doesn't restrict D61.9 as a principal diagnosis.
Is D61.9 a CC or MCC?
- D61.9 is a CC (complication or comorbidity) under MS-DRG v44.0, unless excluded by the principal diagnosis.