ICD-10-CM 2027
ICD-10 code for body fluids exposure
Contact with and (suspected) exposure to potentially hazardous body fluids
From the official ICD-10-CM alphabetic index entry “Exposure (to) › body fluids (potentially hazardous)”. Page updated September 29, 2026.
About coding body fluids exposure
The ICD-10-CM code for body fluids exposure is Z77.21 (Contact with and (suspected) exposure to potentially hazardous body fluids).
Within Z77.2 (contact with and (suspected) exposure to other hazardous substances), Z77.21 is specifically for contact with and (suspected) exposure to potentially hazardous body fluids. Related codes cover environmental tobacco smoke (acute) (chronic) (Z77.22) and other hazardous substances (Z77.29).
It is not a CC or MCC, so as a secondary diagnosis it doesn't change the MS-DRG severity level.
In MS-DRG v44.0, it is part of the grouping logic for DRG 951 (Other Factors Influencing Health Status, relative weight 0.5577), in MDC 23 (Factors Influencing Health Status and Other Contacts with Health Services), as a principal or secondary diagnosis. The DRG a claim lands in depends on the principal diagnosis, procedures and any CC/MCC secondary diagnoses.
Common questions about body fluids exposure ICD-10 codes
What is the ICD-10 code for body fluids exposure?
- Z77.21 — Contact with and (suspected) exposure to potentially hazardous body fluids.
Is Z77.21 billable?
- Yes. Z77.21 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).
Can Z77.21 be used as a principal diagnosis?
- No. It is not acceptable as the principal diagnosis for an inpatient stay; it may be reported as a secondary diagnosis.
Is Z77.21 a CC or MCC?
- No. Z77.21 is neither a CC nor an MCC under MS-DRG v44.0.