ICD-10-CM 2027
ICD-10 code for Calciphylaxis
From the official ICD-10-CM alphabetic index entry “Calciphylaxis”. Page updated September 29, 2026.
About coding Calciphylaxis
The ICD-10-CM code for Calciphylaxis is E83.59 (Other disorders of calcium metabolism).
Within E83.5, choose E83.59 (Other disorders of calcium metabolism) only when documentation doesn't support a more specific option: unspecified disorder of calcium metabolism (E83.50), hypocalcemia (E83.51) and Hypercalcemia (E83.52).
It is not a CC or MCC, so as a secondary diagnosis it doesn't change the MS-DRG severity level.
In MS-DRG v44.0, it is part of the grouping logic for DRG 640 (Miscellaneous Disorders of Nutrition, Metabolism, Fluids and Electrolytes with MCC, relative weight 1.3395) and DRG 641 (Miscellaneous Disorders of Nutrition, Metabolism, Fluids and Electrolytes without MCC, relative weight 0.7865), in MDC 10 (Endocrine, Nutritional and Metabolic Diseases and Disorders), as a principal or secondary diagnosis. The DRG a claim lands in depends on the principal diagnosis, procedures and any CC/MCC secondary diagnoses.
Common questions about Calciphylaxis ICD-10 codes
What is the ICD-10 code for Calciphylaxis?
- E83.59 — Other disorders of calcium metabolism.
Is E83.59 billable?
- Yes. E83.59 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).
Can E83.59 be used as a principal diagnosis?
- Yes. The Medicare Code Editor doesn't restrict E83.59 as a principal diagnosis.
Is E83.59 a CC or MCC?
- No. E83.59 is neither a CC nor an MCC under MS-DRG v44.0.