ICD-10-CM 2027
ICD-10 code for cannabis hyperemesis syndrome
From the official ICD-10-CM alphabetic index entry “Syndrome › cannabis hyperemesis”. Page updated September 29, 2026.
About coding cannabis hyperemesis syndrome
The ICD-10-CM code for cannabis hyperemesis syndrome is R11.16 (Cannabis hyperemesis syndrome).
Within R11.1 (vomiting), R11.16 is specifically for cannabis hyperemesis syndrome. Related codes cover unspecified (R11.10), without nausea (R11.11), Projectile vomiting (R11.12), of fecal matter (R11.13), Bilious vomiting (R11.14) and Cyclical vomiting syndrome unrelated to migraine (R11.15).
It is not a CC or MCC, so as a secondary diagnosis it doesn't change the MS-DRG severity level.
In MS-DRG v44.0, it is part of the grouping logic for DRG 391 (Esophagitis, Gastroenteritis and Miscellaneous Digestive Disorders with MCC, relative weight 1.2392) and DRG 392 (Esophagitis, Gastroenteritis and Miscellaneous Digestive Disorders without MCC, relative weight 0.7645), in MDC 06 (Diseases and Disorders of the Digestive System), as a principal or secondary diagnosis. The DRG a claim lands in depends on the principal diagnosis, procedures and any CC/MCC secondary diagnoses.
Common questions about cannabis hyperemesis syndrome ICD-10 codes
What is the ICD-10 code for cannabis hyperemesis syndrome?
- R11.16 — Cannabis hyperemesis syndrome.
Is R11.16 billable?
- Yes. R11.16 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).
Can R11.16 be used as a principal diagnosis?
- Yes. The Medicare Code Editor doesn't restrict R11.16 as a principal diagnosis.
Is R11.16 a CC or MCC?
- No. R11.16 is neither a CC nor an MCC under MS-DRG v44.0.