ICD-10-CM 2027
ICD-10 code for cerebral depression
From the official ICD-10-CM alphabetic index entry “Depression (acute) (mental) › cerebral”. Page updated September 29, 2026.
About coding cerebral depression
The ICD-10-CM code for cerebral depression is R29.818 (Other symptoms and signs involving the nervous system). The official index lists 1 more specific code, so check the documentation for details such as type, cause, site or severity before settling on R29.818.
Within R29.81, choose R29.818 (Other symptoms and signs involving the nervous system) only when documentation doesn't support a more specific option: facial weakness (R29.810).
It is not a CC or MCC, so as a secondary diagnosis it doesn't change the MS-DRG severity level.
In MS-DRG v44.0, it is part of the grouping logic for DRG 091 (Other Disorders of Nervous System with MCC, relative weight 1.7046), DRG 092 (Other Disorders of Nervous System with CC, relative weight 1.0239) and DRG 093 (Other Disorders of Nervous System without CC/MCC, relative weight 0.7783), in MDC 01 (Diseases and Disorders of the Nervous System), as a principal or secondary diagnosis. The DRG a claim lands in depends on the principal diagnosis, procedures and any CC/MCC secondary diagnoses.
More specific cerebral depression codes (official index)
- newborn P91.4 — Neonatal cerebral depression
Common questions about cerebral depression ICD-10 codes
What is the ICD-10 code for cerebral depression?
- R29.818 — Other symptoms and signs involving the nervous system. More specific codes apply when the documentation supports them: P91.4.
What is the ICD-10 code for newborn cerebral depression?
- P91.4 — Neonatal cerebral depression.
Is R29.818 billable?
- Yes. R29.818 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).
Can R29.818 be used as a principal diagnosis?
- Yes. The Medicare Code Editor doesn't restrict R29.818 as a principal diagnosis.
Is R29.818 a CC or MCC?
- No. R29.818 is neither a CC nor an MCC under MS-DRG v44.0.