ICD-10-CM 2027
ICD-10 code for congenital interstitial emphysema
Interstitial emphysema originating in the perinatal period
From the official ICD-10-CM alphabetic index entry “Emphysema (atrophic) (bullous) (chronic) (interlobular) (lung) (obstructive) (pulmonary) (senile) (vesicular) › congenital (interstitial)”. Page updated September 29, 2026.
About coding congenital interstitial emphysema
The ICD-10-CM code for congenital interstitial emphysema is P25.0 (Interstitial emphysema originating in the perinatal period).
Within P25 (interstitial emphysema and related conditions originating in the perinatal period), P25.0 is specifically for interstitial emphysema originating in the perinatal period. Related codes cover pneumothorax originating in the perinatal period (P25.1), Pneumomediastinum originating in the perinatal period (P25.2), Pneumopericardium originating in the perinatal period (P25.3) and other conditions related to interstitial emphysema originating in the perinatal period (P25.8).
As a secondary diagnosis it is an MCC (major complication or comorbidity), which can move an inpatient stay into the highest-paying "with MCC" MS-DRG of its family, unless the principal diagnosis excludes it.
In MS-DRG v44.0, it is part of the grouping logic for DRG 791 (Prematurity with Major Problems, relative weight 4.1075) and DRG 793 (Full Term Neonate with Major Problems, relative weight 4.2195), in MDC 15 (Newborns and Other Neonates with Conditions Originating in the Perinatal Period), as a principal or secondary diagnosis. The DRG a claim lands in depends on the principal diagnosis, procedures and any CC/MCC secondary diagnoses.
Common questions about congenital interstitial emphysema ICD-10 codes
What is the ICD-10 code for congenital interstitial emphysema?
- P25.0 — Interstitial emphysema originating in the perinatal period.
Is P25.0 billable?
- Yes. P25.0 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).
Can P25.0 be used as a principal diagnosis?
- Yes. The Medicare Code Editor doesn't restrict P25.0 as a principal diagnosis.
Is P25.0 a CC or MCC?
- P25.0 is an MCC (major complication or comorbidity) under MS-DRG v44.0, unless excluded by the principal diagnosis.