ICD-10-CM 2027
ICD-10 code for defibrination
Disseminated intravascular coagulation [defibrination syndrome]
From the official ICD-10-CM alphabetic index entry “Defibrination (syndrome)”. Page updated September 29, 2026.
About coding defibrination
The ICD-10-CM code for defibrination is D65 (Disseminated intravascular coagulation [defibrination syndrome]). The official index lists 4 more specific codes, so check the documentation for details such as type, cause, site or severity before settling on D65.
Don't report D65 together with the conditions in its Excludes1 note: in newborn (P60) and pregnancy, childbirth and the puerperium (O45.0, O46.0, O67.0, O72.3).
The conditions in its Excludes2 note aren't part of D65, but may be coded alongside it if the patient has both: abortion or ectopic or molar pregnancy (O00-O07, O08.1).
As a secondary diagnosis it is an MCC (major complication or comorbidity), which can move an inpatient stay into the highest-paying "with MCC" MS-DRG of its family, unless the principal diagnosis excludes it.
More specific defibrination codes (official index)
- antepartum
- following ectopic or molar pregnancy O08.1 — Delayed or excessive hemorrhage following ectopic and molar pregnancy
- intrapartum O67.0 — Intrapartum hemorrhage with coagulation defect
- newborn P60 — Disseminated intravascular coagulation of newborn
- postpartum O72.3 — Postpartum coagulation defects
Don't confuse with (Excludes1 for D65)
Common questions about defibrination ICD-10 codes
What is the ICD-10 code for defibrination?
- D65 — Disseminated intravascular coagulation [defibrination syndrome]. More specific codes apply when the documentation supports them: O08.1, O67.0, P60, O72.3.
What is the ICD-10 code for intrapartum defibrination?
- O67.0 — Intrapartum hemorrhage with coagulation defect.
What is the ICD-10 code for newborn defibrination?
- P60 — Disseminated intravascular coagulation of newborn.
What is the ICD-10 code for postpartum defibrination?
- O72.3 — Postpartum coagulation defects.
Is D65 billable?
- Yes. D65 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).
Can D65 be used as a principal diagnosis?
- Yes. The Medicare Code Editor doesn't restrict D65 as a principal diagnosis.
Is D65 a CC or MCC?
- D65 is an MCC (major complication or comorbidity) under MS-DRG v44.0, unless excluded by the principal diagnosis.