ICD-10-CM 2027
ICD-10 code for delirium
From the official ICD-10-CM alphabetic index entry “Delirium, delirious (acute or subacute) (not alcohol- or drug-induced)”. Page updated September 29, 2026.
About coding delirium
The ICD-10-CM code for delirium is R41.0 (Disorientation, unspecified). The official index lists 55 more specific codes, so check the documentation for details such as type, cause, site or severity before settling on R41.0.
Within R41, choose R41.0 (Disorientation, unspecified) only when documentation doesn't support a more specific option: Anterograde amnesia (R41.1), retrograde amnesia (R41.2), other amnesia (R41.3), neurologic neglect syndrome (R41.4), other symptoms and signs involving cognitive functions and awareness (R41.8) and unspecified symptoms and signs involving cognitive functions and awareness (R41.9).
Don't report R41.0 together with the conditions in its Excludes1 note: delirium due to known physiological condition (F05).
It is not a CC or MCC, so as a secondary diagnosis it doesn't change the MS-DRG severity level.
More specific delirium codes (official index)
- with
- dementia F05 — Delirium due to known physiological condition
- alcoholic (acute) (tremens) (withdrawal) F10.921 — Alcohol use, unspecified with intoxication delirium
- with intoxication F10.921 — Alcohol use, unspecified with intoxication delirium
- in
- abuse F10.121 — Alcohol abuse with intoxication delirium
- dependence F10.221 — Alcohol dependence with intoxication delirium
- due to (secondary to)
- alcohol
- intoxication F10.921 — Alcohol use, unspecified with intoxication delirium
- in
- abuse F10.121 — Alcohol abuse with intoxication delirium
- dependence F10.221 — Alcohol dependence with intoxication delirium
- withdrawal F10.231 — Alcohol dependence with withdrawal delirium
- amphetamine intoxication F15.921 — Other stimulant use, unspecified with intoxication delirium
- in
- abuse F15.121 — Other stimulant abuse with intoxication delirium
- dependence F15.221 — Other stimulant dependence with intoxication delirium
- anxiolytic
- intoxication F13.921 — Sedative, hypnotic or anxiolytic use, unspecified with intoxication delirium
- in
- abuse F13.121 — Sedative, hypnotic or anxiolytic abuse with intoxication delirium
- dependence F13.221 — Sedative, hypnotic or anxiolytic dependence with intoxication delirium
- withdrawal F13.231 — Sedative, hypnotic or anxiolytic dependence with withdrawal delirium
- cannabis intoxication (acute) F12.921 — Cannabis use, unspecified with intoxication delirium
- in
- abuse F12.121 — Cannabis abuse with intoxication delirium
- dependence F12.221 — Cannabis dependence with intoxication delirium
- cocaine intoxication (acute) F14.921 — Cocaine use, unspecified with intoxication delirium
- in
- abuse F14.121 — Cocaine abuse with intoxication with delirium
- dependence F14.221 — Cocaine dependence with intoxication delirium
- general medical condition F05 — Delirium due to known physiological condition
- hallucinogen intoxication F16.921 — Hallucinogen use, unspecified with intoxication with delirium
- in
- abuse F16.121 — Hallucinogen abuse with intoxication with delirium
- dependence F16.221 — Hallucinogen dependence with intoxication with delirium
- hypnotic
- intoxication F13.921 — Sedative, hypnotic or anxiolytic use, unspecified with intoxication delirium
- in
- abuse F13.121 — Sedative, hypnotic or anxiolytic abuse with intoxication delirium
- dependence F13.221 — Sedative, hypnotic or anxiolytic dependence with intoxication delirium
- withdrawal F13.231 — Sedative, hypnotic or anxiolytic dependence with withdrawal delirium
- inhalant intoxication (acute) F18.921 — Inhalant use, unspecified with intoxication with delirium
- in
- abuse F18.121 — Inhalant abuse with intoxication delirium
- dependence F18.221 — Inhalant dependence with intoxication delirium
- multiple etiologies F05 — Delirium due to known physiological condition
- opioid intoxication (acute) F11.921 — Opioid use, unspecified with intoxication delirium
- in
- abuse F11.121 — Opioid abuse with intoxication delirium
- dependence F11.221 — Opioid dependence with intoxication delirium
- other (or unknown) substance F19.921 — Other psychoactive substance use, unspecified with intoxication with delirium
- phencyclidine intoxication (acute) F16.921 — Hallucinogen use, unspecified with intoxication with delirium
- in
- abuse F16.121 — Hallucinogen abuse with intoxication with delirium
- dependence F16.221 — Hallucinogen dependence with intoxication with delirium
- psychoactive substance NEC intoxication (acute) F19.921 — Other psychoactive substance use, unspecified with intoxication with delirium
- in
- abuse F19.121 — Other psychoactive substance abuse with intoxication delirium
- dependence F19.221 — Other psychoactive substance dependence with intoxication delirium
- sedative
- intoxication F13.921 — Sedative, hypnotic or anxiolytic use, unspecified with intoxication delirium
- in
- abuse F13.121 — Sedative, hypnotic or anxiolytic abuse with intoxication delirium
- dependence F13.221 — Sedative, hypnotic or anxiolytic dependence with intoxication delirium
- withdrawal F13.231 — Sedative, hypnotic or anxiolytic dependence with withdrawal delirium
- unknown etiology R41.0 — Disorientation, unspecified
- exhaustion F43.0 — Acute stress reaction
- hysterical F44.89 — Other dissociative and conversion disorders
- postprocedural (postoperative) F05 — Delirium due to known physiological condition
- puerperal F05 — Delirium due to known physiological condition
- thyroid
- traumatic
- tremens (alcohol-induced) F10.231 — Alcohol dependence with withdrawal delirium
- sedative-induced F13.231 — Sedative, hypnotic or anxiolytic dependence with withdrawal delirium
Don't confuse with (Excludes1 for R41.0)
- delirium due to known physiological condition (F05)
Common questions about delirium ICD-10 codes
What is the ICD-10 code for delirium?
- R41.0 — Disorientation, unspecified. More specific codes apply when the documentation supports them: F05, F10.921, F10.921, F10.121 and others below.
What is the ICD-10 code for alcoholic delirium?
- F10.921 — Alcohol use, unspecified with intoxication delirium.
What is the ICD-10 code for exhaustion delirium?
- F43.0 — Acute stress reaction.
What is the ICD-10 code for hysterical delirium?
- F44.89 — Other dissociative and conversion disorders.
What is the ICD-10 code for postprocedural delirium?
- F05 — Delirium due to known physiological condition.
What is the ICD-10 code for puerperal delirium?
- F05 — Delirium due to known physiological condition.
What is the ICD-10 code for tremens delirium?
- F10.231 — Alcohol dependence with withdrawal delirium.
Is R41.0 billable?
- Yes. R41.0 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).
Can R41.0 be used as a principal diagnosis?
- Yes. The Medicare Code Editor doesn't restrict R41.0 as a principal diagnosis.
Is R41.0 a CC or MCC?
- No. R41.0 is neither a CC nor an MCC under MS-DRG v44.0.