ICD-10-CM 2027
ICD-10 code for drug rash
From the official ICD-10-CM alphabetic index entry “Rash (toxic) › drug (internal use)”. Page updated September 29, 2026.
About coding drug rash
The ICD-10-CM code for drug rash is L27.0 (Generalized skin eruption due to drugs and medicaments taken internally). The official index lists 1 more specific code, so check the documentation for details such as type, cause, site or severity before settling on L27.0.
Within L27 (dermatitis due to substances taken internally), L27.0 is specifically for generalized skin eruption due to drugs and medicaments taken internally. Related codes cover localized skin eruption due to drugs and medicaments taken internally (L27.1), dermatitis due to ingested food (L27.2), dermatitis due to other substances taken internally (L27.8) and dermatitis due to unspecified substance taken internally (L27.9).
Use an additional code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5).
It is not a CC or MCC, so as a secondary diagnosis it doesn't change the MS-DRG severity level.
More specific drug rash codes (official index)
- contact L25.1 — Unspecified contact dermatitis due to drugs in contact with skin
Common questions about drug rash ICD-10 codes
What is the ICD-10 code for drug rash?
- L27.0 — Generalized skin eruption due to drugs and medicaments taken internally. More specific codes apply when the documentation supports them: L25.1.
What is the ICD-10 code for contact drug rash?
- L25.1 — Unspecified contact dermatitis due to drugs in contact with skin.
Is L27.0 billable?
- Yes. L27.0 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).
Can L27.0 be used as a principal diagnosis?
- Yes. The Medicare Code Editor doesn't restrict L27.0 as a principal diagnosis.
Is L27.0 a CC or MCC?
- No. L27.0 is neither a CC nor an MCC under MS-DRG v44.0.