ICD-10-CM 2027
ICD-10 code for elevated PSA
Elevated prostate specific antigen [PSA]
Confirmed by the official ICD-10-CM index entry “elevated, elevation › prostate specific antigen [psa]”. Page updated September 29, 2026.
About coding elevated PSA
The ICD-10-CM code for elevated PSA is R97.20 (Elevated prostate specific antigen [PSA]). The official index lists 1 more specific code, so check the documentation for details such as type, cause, site or severity before settling on R97.20.
Within R97.2 (elevated prostate specific antigen [PSA]), R97.20 is specifically for elevated prostate specific antigen [PSA]. Related codes cover Rising PSA following treatment for malignant neoplasm of prostate (R97.21).
It is not a CC or MCC, so as a secondary diagnosis it doesn't change the MS-DRG severity level.
In MS-DRG v44.0, it is part of the grouping logic for DRG 947 (Signs and Symptoms with MCC, relative weight 1.261) and DRG 948 (Signs and Symptoms without MCC, relative weight 0.7835), in MDC 23 (Factors Influencing Health Status and Other Contacts with Health Services), as a principal or secondary diagnosis. The DRG a claim lands in depends on the principal diagnosis, procedures and any CC/MCC secondary diagnoses.
Related Elevated PSA codes
- R97.21 Rising PSA following treatment for malignant neoplasm of prostate
Common questions about elevated PSA ICD-10 codes
What is the ICD-10 code for elevated PSA?
- R97.20 — Elevated prostate specific antigen [PSA]. More specific codes apply when the documentation supports them: R97.21.
What is the ICD-10 code for rising psa following treatment for malignant neoplasm of prostate?
- R97.21 — Rising PSA following treatment for malignant neoplasm of prostate.
Is R97.20 billable?
- Yes. R97.20 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).
Can R97.20 be used as a principal diagnosis?
- It can, but When it is the principal diagnosis, Medicare considers it a questionable reason for an inpatient admission, so claims may be reviewed.
Is R97.20 a CC or MCC?
- No. R97.20 is neither a CC nor an MCC under MS-DRG v44.0.