ICD-10-CM 2027
ICD-10 code for Eosinophilia-myalgia syndrome
Other specified systemic involvement of connective tissue
From the official ICD-10-CM alphabetic index entry “Eosinophilia-myalgia syndrome”. Page updated September 29, 2026.
About coding Eosinophilia-myalgia syndrome
The ICD-10-CM code for Eosinophilia-myalgia syndrome is M35.89 (Other specified systemic involvement of connective tissue).
Within M35.8, choose M35.89 (Other specified systemic involvement of connective tissue) only when documentation doesn't support a more specific option: Multisystem inflammatory syndrome (M35.81).
As a secondary diagnosis it is a CC (complication or comorbidity), which can move an inpatient stay into the "with CC" MS-DRG of its family, unless the principal diagnosis excludes it.
In MS-DRG v44.0, it is part of the grouping logic for DRG 545 (Connective Tissue Disorders with MCC, relative weight 2.3892), DRG 546 (Connective Tissue Disorders with CC, relative weight 1.1745) and DRG 547 (Connective Tissue Disorders without CC/MCC, relative weight 0.7526), in MDC 08 (Diseases and Disorders of the Musculoskeletal System and Connective Tissue), as a principal or secondary diagnosis. The DRG a claim lands in depends on the principal diagnosis, procedures and any CC/MCC secondary diagnoses.
Common questions about Eosinophilia-myalgia syndrome ICD-10 codes
What is the ICD-10 code for Eosinophilia-myalgia syndrome?
- M35.89 — Other specified systemic involvement of connective tissue.
Is M35.89 billable?
- Yes. M35.89 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).
Can M35.89 be used as a principal diagnosis?
- Yes. The Medicare Code Editor doesn't restrict M35.89 as a principal diagnosis.
Is M35.89 a CC or MCC?
- M35.89 is a CC (complication or comorbidity) under MS-DRG v44.0, unless excluded by the principal diagnosis.