ICD-10-CM 2027
ICD-10 code for gangliosidosis
From the official ICD-10-CM alphabetic index entry “Gangliosidosis”. Page updated September 29, 2026.
About coding gangliosidosis
The ICD-10-CM code for gangliosidosis is E75.10 (Unspecified gangliosidosis). The official index lists 7 more specific codes, so check the documentation for details such as type, cause, site or severity before settling on E75.10.
Within E75.1, choose E75.10 (Unspecified gangliosidosis) only when documentation doesn't support a more specific option: Mucolipidosis IV (E75.11) and other gangliosidosis (E75.19).
As a secondary diagnosis it is a CC (complication or comorbidity), which can move an inpatient stay into the "with CC" MS-DRG of its family, unless the principal diagnosis excludes it.
In MS-DRG v44.0, it is part of the grouping logic for DRG 056 (Degenerative Nervous System Disorders with MCC, relative weight 2.2655) and DRG 057 (Degenerative Nervous System Disorders without MCC, relative weight 1.2838), in MDC 01 (Diseases and Disorders of the Nervous System), as a principal or secondary diagnosis. The DRG a claim lands in depends on the principal diagnosis, procedures and any CC/MCC secondary diagnoses.
More specific gangliosidosis codes (official index)
Common questions about gangliosidosis ICD-10 codes
What is the ICD-10 code for gangliosidosis?
- E75.10 — Unspecified gangliosidosis. More specific codes apply when the documentation supports them: E75.19, E75.00, E75.09, E75.01 and others below.
What is the ICD-10 code for gm1 gangliosidosis?
- E75.19 — Other gangliosidosis.
What is the ICD-10 code for gm2 gangliosidosis?
- E75.00 — GM2 gangliosidosis, unspecified.
What is the ICD-10 code for gm3 gangliosidosis?
- E75.19 — Other gangliosidosis.
What is the ICD-10 code for mucolipidosis iv gangliosidosis?
- E75.11 — Mucolipidosis IV.
Is E75.10 billable?
- Yes. E75.10 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).
Can E75.10 be used as a principal diagnosis?
- Yes. The Medicare Code Editor doesn't restrict E75.10 as a principal diagnosis.
Is E75.10 a CC or MCC?
- E75.10 is a CC (complication or comorbidity) under MS-DRG v44.0, unless excluded by the principal diagnosis.