ICD-10-CM 2027
ICD-10 code for Hairy cell leukemia
From the official ICD-10-CM alphabetic index entry “Leukemia, leukemic › hairy cell”. Page updated September 29, 2026.
About coding Hairy cell leukemia
The ICD-10-CM code for Hairy cell leukemia is C91.4 (Hairy cell leukemia).
Within C91 (lymphoid leukemia), C91.4 is specifically for Hairy cell leukemia. Related codes cover acute lymphoblastic leukemia [ALL] (C91.0), chronic lymphocytic leukemia of B-cell type (C91.1), Prolymphocytic leukemia of B-cell type (C91.3), adult T-cell lymphoma/leukemia (HTLV-1-associated) (C91.5), Prolymphocytic leukemia of T-cell type (C91.6), unspecified (C91.9), mature B-cell leukemia Burkitt-type (C91.A) and other lymphoid leukemia (C91.Z).
To report this condition, pick the subcode that matches the documentation: C91.40 (not having achieved remission), C91.41 (in remission) and C91.42 (in relapse).
It has been part of ICD-10-CM since the code set took effect on October 1, 2015 and hasn't changed since.