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ICD-10-CM 2027

ICD-10 code for herpesviral hepatitis

B00.81

Herpesviral hepatitis

✓ Billable / specificCC — complication/comorbidity

From the official ICD-10-CM alphabetic index entry “Hepatitis › herpesviral”. Page updated September 29, 2026.

About coding herpesviral hepatitis

The ICD-10-CM code for herpesviral hepatitis is B00.81 (Herpesviral hepatitis).

Within B00.8 (other forms of herpesviral infections), B00.81 is specifically for herpesviral hepatitis. Related codes cover herpes simplex myelitis (B00.82) and other herpesviral infection (B00.89).

As a secondary diagnosis it is a CC (complication or comorbidity), which can move an inpatient stay into the "with CC" MS-DRG of its family, unless the principal diagnosis excludes it.

In MS-DRG v44.0, it is part of the grouping logic for DRG 393 (Other Digestive System Diagnoses with MCC, relative weight 1.5881), DRG 394 (Other Digestive System Diagnoses with CC, relative weight 0.9228), DRG 395 (Other Digestive System Diagnoses without CC/MCC, relative weight 0.6382), DRG 791 (Prematurity with Major Problems, relative weight 4.1075), DRG 793 (Full Term Neonate with Major Problems, relative weight 4.2195), DRG 974 (HIV with Major Related Condition with MCC, relative weight 3.0506) and 2 more, in MDC 06 (Diseases and Disorders of the Digestive System), MDC 15 (Newborns and Other Neonates with Conditions Originating in the Perinatal Period) and MDC 25 (Human Immunodeficiency Virus Infections), as a principal or secondary diagnosis. The DRG a claim lands in depends on the principal diagnosis, procedures and any CC/MCC secondary diagnoses.

Common questions about herpesviral hepatitis ICD-10 codes

What is the ICD-10 code for herpesviral hepatitis?

B00.81 — Herpesviral hepatitis.

Is B00.81 billable?

Yes. B00.81 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).

Can B00.81 be used as a principal diagnosis?

Yes. The Medicare Code Editor doesn't restrict B00.81 as a principal diagnosis.

Is B00.81 a CC or MCC?

B00.81 is a CC (complication or comorbidity) under MS-DRG v44.0, unless excluded by the principal diagnosis.