ICD-10 code for histiocytosis

The ICD-10-CM code for histiocytosis is D76.3 (Other histiocytosis syndromes). The official index lists 21 more specific codes, so check the documentation for details such as type, cause, site or severity before settling on D76.3.

Within D76, choose D76.3 (Other histiocytosis syndromes) only when documentation doesn't support a more specific option: Hemophagocytic lymphohistiocytosis (D76.1) and Hemophagocytic syndrome, infection-associated (D76.2).

As a secondary diagnosis it is a CC (complication or comorbidity), which can move an inpatient stay into the "with CC" MS-DRG of its family, unless the principal diagnosis excludes it.

In MS-DRG v44.0, it is part of the grouping logic for DRG 814 (Reticuloendothelial and Immunity Disorders with MCC, relative weight 2.0729), DRG 815 (Reticuloendothelial and Immunity Disorders with CC, relative weight 1.0444) and DRG 816 (Reticuloendothelial and Immunity Disorders without CC/MCC, relative weight 0.7381), in MDC 16 (Diseases and Disorders of the Blood and Blood Forming Organs and Immunological Disorders), as a principal or secondary diagnosis. The DRG a claim lands in depends on the principal diagnosis, procedures and any CC/MCC secondary diagnoses.