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ICD-10-CM 2027

ICD-10 code for human papillomavirus screening

Z11.51

Encounter for screening for human papillomavirus (HPV)

✓ Billable / specificNot a principal dx

From the official ICD-10-CM alphabetic index entry “Screening (for) › human papillomavirus”. Page updated September 29, 2026.

About coding human papillomavirus screening

The ICD-10-CM code for human papillomavirus screening is Z11.51 (Encounter for screening for human papillomavirus (HPV)).

Within Z11.5 (encounter for screening for other viral diseases), Z11.51 is specifically for encounter for screening for human papillomavirus (HPV). Related codes cover COVID-19 (Z11.52) and other viral diseases (Z11.59).

It is not a CC or MCC, so as a secondary diagnosis it doesn't change the MS-DRG severity level.

In MS-DRG v44.0, it is part of the grouping logic for DRG 951 (Other Factors Influencing Health Status, relative weight 0.5577), in MDC 23 (Factors Influencing Health Status and Other Contacts with Health Services), as a principal or secondary diagnosis. The DRG a claim lands in depends on the principal diagnosis, procedures and any CC/MCC secondary diagnoses.

Common questions about human papillomavirus screening ICD-10 codes

What is the ICD-10 code for human papillomavirus screening?

Z11.51 — Encounter for screening for human papillomavirus (HPV).

Is Z11.51 billable?

Yes. Z11.51 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).

Can Z11.51 be used as a principal diagnosis?

No. It is not acceptable as the principal diagnosis for an inpatient stay; it may be reported as a secondary diagnosis.

Is Z11.51 a CC or MCC?

No. Z11.51 is neither a CC nor an MCC under MS-DRG v44.0.