ICD-10-CM 2027
ICD-10 code for Hyperglobulinemia
From the official ICD-10-CM alphabetic index entry “Hyperglobulinemia”. Page updated September 29, 2026.
About coding Hyperglobulinemia
The ICD-10-CM code for Hyperglobulinemia is R77.1 (Abnormality of globulin).
Within R77 (other abnormalities of plasma proteins), R77.1 is specifically for abnormality of globulin. Related codes cover abnormality of albumin (R77.0), abnormality of alphafetoprotein (R77.2), other specified abnormalities of plasma proteins (R77.8) and abnormality of plasma protein, unspecified (R77.9).
It is not a CC or MCC, so as a secondary diagnosis it doesn't change the MS-DRG severity level.
In MS-DRG v44.0, it is part of the grouping logic for DRG 947 (Signs and Symptoms with MCC, relative weight 1.261) and DRG 948 (Signs and Symptoms without MCC, relative weight 0.7835), in MDC 23 (Factors Influencing Health Status and Other Contacts with Health Services), as a principal or secondary diagnosis. The DRG a claim lands in depends on the principal diagnosis, procedures and any CC/MCC secondary diagnoses.
Common questions about Hyperglobulinemia ICD-10 codes
What is the ICD-10 code for Hyperglobulinemia?
- R77.1 — Abnormality of globulin.
Is R77.1 billable?
- Yes. R77.1 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).
Can R77.1 be used as a principal diagnosis?
- Yes. The Medicare Code Editor doesn't restrict R77.1 as a principal diagnosis.
Is R77.1 a CC or MCC?
- No. R77.1 is neither a CC nor an MCC under MS-DRG v44.0.