ICD-10 code for Hyperphenylalaninemia NEC

The ICD-10-CM code for Hyperphenylalaninemia NEC is E70.1 (Other hyperphenylalaninemias).

Within E70, choose E70.1 (Other hyperphenylalaninemias) only when documentation doesn't support a more specific option: classical phenylketonuria (E70.0), disorders of tyrosine metabolism (E70.2), albinism (E70.3), disorders of histidine metabolism (E70.4), disorders of tryptophan metabolism (E70.5), other disorders of aromatic amino-acid metabolism (E70.8) and disorder of aromatic amino-acid metabolism, unspecified (E70.9).

As a secondary diagnosis it is a CC (complication or comorbidity), which can move an inpatient stay into the "with CC" MS-DRG of its family, unless the principal diagnosis excludes it.

In MS-DRG v44.0, it is part of the grouping logic for DRG 642 (Inborn and Other Disorders of Metabolism, relative weight 1.3219), in MDC 10 (Endocrine, Nutritional and Metabolic Diseases and Disorders), as a principal or secondary diagnosis. The DRG a claim lands in depends on the principal diagnosis, procedures and any CC/MCC secondary diagnoses.