ICD-10-CM 2027
ICD-10 code for II albinism
Tyrosinase positive oculocutaneous albinism
From the official ICD-10-CM alphabetic index entry “Albinism, albino › II”. Page updated September 29, 2026.
About coding II albinism
The ICD-10-CM code for II albinism is E70.321 (Tyrosinase positive oculocutaneous albinism).
Within E70.32 (oculocutaneous albinism), E70.321 is specifically for Tyrosinase positive oculocutaneous albinism. Related codes cover Tyrosinase negative oculocutaneous albinism (E70.320), other oculocutaneous albinism (E70.328) and unspecified (E70.329).
As a secondary diagnosis it is a CC (complication or comorbidity), which can move an inpatient stay into the "with CC" MS-DRG of its family, unless the principal diagnosis excludes it.
In MS-DRG v44.0, it is part of the grouping logic for DRG 642 (Inborn and Other Disorders of Metabolism, relative weight 1.3219), in MDC 10 (Endocrine, Nutritional and Metabolic Diseases and Disorders), as a principal or secondary diagnosis. The DRG a claim lands in depends on the principal diagnosis, procedures and any CC/MCC secondary diagnoses.
Common questions about II albinism ICD-10 codes
What is the ICD-10 code for II albinism?
- E70.321 — Tyrosinase positive oculocutaneous albinism.
Is E70.321 billable?
- Yes. E70.321 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).
Can E70.321 be used as a principal diagnosis?
- Yes. The Medicare Code Editor doesn't restrict E70.321 as a principal diagnosis.
Is E70.321 a CC or MCC?
- E70.321 is a CC (complication or comorbidity) under MS-DRG v44.0, unless excluded by the principal diagnosis.