ICD-10-CM 2027
ICD-10 code for infection mssa
Methicillin susceptible Staphylococcus aureus infection, unspecified site
From the official ICD-10-CM alphabetic index entry “MSSA (Methicillin susceptible Staphylococcus aureus) › infection”. Page updated September 29, 2026.
About coding infection mssa
The ICD-10-CM code for infection mssa is A49.01 (Methicillin susceptible Staphylococcus aureus infection, unspecified site). The official index lists 1 more specific code, so check the documentation for details such as type, cause, site or severity before settling on A49.01.
Within A49.0, choose A49.01 (susceptible Staphylococcus aureus infection, unspecified site) only when documentation doesn't support a more specific option: resistant Staphylococcus aureus infection, unspecified site (A49.02).
It is not a CC or MCC, so as a secondary diagnosis it doesn't change the MS-DRG severity level.
In MS-DRG v44.0, it is part of the grouping logic for DRG 867 (Other Infectious and Parasitic Diseases Diagnoses with MCC, relative weight 2.1859), DRG 868 (Other Infectious and Parasitic Diseases Diagnoses with CC, relative weight 1.0235) and DRG 869 (Other Infectious and Parasitic Diseases Diagnoses without CC/MCC, relative weight 0.6787), in MDC 18 (Infectious and Parasitic Diseases, Systemic or Unspecified Sites), as a principal or secondary diagnosis. The DRG a claim lands in depends on the principal diagnosis, procedures and any CC/MCC secondary diagnoses.
More specific infection mssa codes (official index)
- as the cause of diseases classified elsewhere B95.61 — Methicillin susceptible Staphylococcus aureus infection as the cause of diseases classified elsewhere
Common questions about infection mssa ICD-10 codes
What is the ICD-10 code for infection mssa?
- A49.01 — Methicillin susceptible Staphylococcus aureus infection, unspecified site. More specific codes apply when the documentation supports them: B95.61.
Is A49.01 billable?
- Yes. A49.01 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).
Can A49.01 be used as a principal diagnosis?
- Yes. The Medicare Code Editor doesn't restrict A49.01 as a principal diagnosis.
Is A49.01 a CC or MCC?
- No. A49.01 is neither a CC nor an MCC under MS-DRG v44.0.