ICD-10-CM 2027
ICD-10 code for insulin reaction
Poisoning by, adverse effect of and underdosing of insulin and oral hypoglycemic [antidiabetic] drugs
From the official ICD-10-CM alphabetic index entry “Reaction › insulin”. Page updated September 29, 2026.
About coding insulin reaction
The ICD-10-CM code for insulin reaction is T38.3 (Poisoning by, adverse effect of and underdosing of insulin and oral hypoglycemic [antidiabetic] drugs).
Within T38 (poisoning by, adverse effect of and underdosing of hormones and their synthetic substitutes and antagonists, not elsewhere classified), T38.3 is specifically for poisoning by, adverse effect of and underdosing of insulin and oral hypoglycemic [antidiabetic] drugs. Related codes cover glucocorticoids and synthetic analogues (T38.0), thyroid hormones and substitutes (T38.1), antithyroid drugs (T38.2), oral contraceptives (T38.4), other estrogens and progestogens (T38.5), antigonadotrophins, antiestrogens, antiandrogens, not elsewhere classified (T38.6), androgens and anabolic congeners (T38.7), other and unspecified hormones and synthetic substitutes (T38.8) and 1 more.
Codes in this range require a 7th character: A for initial encounter, D for subsequent encounter and S for sequela. Use placeholder "X" characters to fill any empty positions before the 7th character.
It has been part of ICD-10-CM since the code set took effect on October 1, 2015 and hasn't changed since.