ICD-10-CM 2027
ICD-10 code for insulin shock
From the official ICD-10-CM alphabetic index entry “Shock › insulin”. Page updated September 29, 2026.
About coding insulin shock
The ICD-10-CM code for insulin shock is E15 (Nondiabetic hypoglycemic coma).
As a secondary diagnosis it is a CC (complication or comorbidity), which can move an inpatient stay into the "with CC" MS-DRG of its family, unless the principal diagnosis excludes it.
In MS-DRG v44.0, it is part of the grouping logic for DRG 640 (Miscellaneous Disorders of Nutrition, Metabolism, Fluids and Electrolytes with MCC, relative weight 1.3395), DRG 641 (Miscellaneous Disorders of Nutrition, Metabolism, Fluids and Electrolytes without MCC, relative weight 0.7865), DRG 791 (Prematurity with Major Problems, relative weight 4.1075) and DRG 793 (Full Term Neonate with Major Problems, relative weight 4.2195), in MDC 10 (Endocrine, Nutritional and Metabolic Diseases and Disorders) and MDC 15 (Newborns and Other Neonates with Conditions Originating in the Perinatal Period), as a principal or secondary diagnosis. The DRG a claim lands in depends on the principal diagnosis, procedures and any CC/MCC secondary diagnoses.
It has been part of ICD-10-CM since the code set took effect on October 1, 2015 and hasn't changed since.
More specific insulin shock codes (official index)
- therapeutic misadventure
Common questions about insulin shock ICD-10 codes
What is the ICD-10 code for insulin shock?
- E15 — Nondiabetic hypoglycemic coma.
Is E15 billable?
- Yes. E15 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).
Can E15 be used as a principal diagnosis?
- Yes. The Medicare Code Editor doesn't restrict E15 as a principal diagnosis.
Is E15 a CC or MCC?
- E15 is a CC (complication or comorbidity) under MS-DRG v44.0, unless excluded by the principal diagnosis.