ICD-10-CM 2027
ICD-10 code for Interventricular septal defect
From the official ICD-10-CM alphabetic index entry “Defect, defective › interventricular septal”. Page updated September 29, 2026.
About coding Interventricular septal defect
The ICD-10-CM code for Interventricular septal defect is Q21.0 (Ventricular septal defect). The official index lists 2 more specific codes, so check the documentation for details such as type, cause, site or severity before settling on Q21.0.
Within Q21 (congenital malformations of cardiac septa), Q21.0 is specifically for ventricular septal defect. Related codes cover atrial septal defect (Q21.1), atrioventricular septal defect (Q21.2), tetralogy of Fallot (Q21.3), Aortopulmonary septal defect (Q21.4), other congenital malformations of cardiac septa (Q21.8) and congenital malformation of cardiac septum, unspecified (Q21.9).
As a secondary diagnosis it is a CC (complication or comorbidity), which can move an inpatient stay into the "with CC" MS-DRG of its family, unless the principal diagnosis excludes it.
In MS-DRG v44.0, it is part of the grouping logic for DRG 306 (Cardiac Congenital and Valvular Disorders with MCC, relative weight 1.546), DRG 307 (Cardiac Congenital and Valvular Disorders without MCC, relative weight 0.9148), DRG 791 (Prematurity with Major Problems, relative weight 4.1075) and DRG 793 (Full Term Neonate with Major Problems, relative weight 4.2195), in MDC 05 (Diseases and Disorders of the Circulatory System) and MDC 15 (Newborns and Other Neonates with Conditions Originating in the Perinatal Period), as a principal or secondary diagnosis. The DRG a claim lands in depends on the principal diagnosis, procedures and any CC/MCC secondary diagnoses.
More specific Interventricular septal defect codes (official index)
Common questions about Interventricular septal defect ICD-10 codes
What is the ICD-10 code for Interventricular septal defect?
- Q21.0 — Ventricular septal defect. More specific codes apply when the documentation supports them: Q21.3, Q21.3.
Is Q21.0 billable?
- Yes. Q21.0 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).
Can Q21.0 be used as a principal diagnosis?
- Yes. The Medicare Code Editor doesn't restrict Q21.0 as a principal diagnosis.
Is Q21.0 a CC or MCC?
- Q21.0 is a CC (complication or comorbidity) under MS-DRG v44.0, unless excluded by the principal diagnosis.