ICD-10-CM 2027
ICD-10 code for isolated proteinuria
From the official ICD-10-CM alphabetic index entry “Proteinuria › isolated”. Page updated September 29, 2026.
About coding isolated proteinuria
The ICD-10-CM code for isolated proteinuria is R80.0 (Isolated proteinuria). The official index lists 14 more specific codes, so check the documentation for details such as type, cause, site or severity before settling on R80.0.
Within R80 (proteinuria), R80.0 is specifically for isolated proteinuria. Related codes cover persistent proteinuria, unspecified (R80.1), orthostatic proteinuria, unspecified (R80.2), Bence Jones proteinuria (R80.3), other proteinuria (R80.8) and unspecified (R80.9).
Don't report R80.0 together with the conditions in its Excludes1 note: isolated proteinuria with specific morphological lesion (N06.-).
It is not a CC or MCC, so as a secondary diagnosis it doesn't change the MS-DRG severity level.
More specific isolated proteinuria codes (official index)
- with glomerular lesion N06.9 — Isolated proteinuria with unspecified morphologic lesion
- C3
- glomerulonephritis N06.A — Isolated proteinuria with C3 glomerulonephritis
- glomerulopathy N06.A — Isolated proteinuria with C3 glomerulonephritis
- with dense deposit disease N06.6 — Isolated proteinuria with dense deposit disease
- dense deposit disease N06.6 — Isolated proteinuria with dense deposit disease
- diffuse
- crescentic glomerulonephritis N06.7 — Isolated proteinuria with diffuse crescentic glomerulonephritis
- endocapillary proliferative glomerulonephritis N06.4 — Isolated proteinuria with diffuse endocapillary proliferative glomerulonephritis
- mesangiocapillary glomerulonephritis N06.5 — Isolated proteinuria with diffuse mesangiocapillary glomerulonephritis
- focal and segmental hyalinosis or sclerosis N06.1 — Isolated proteinuria with focal and segmental glomerular lesions
- membranous (diffuse) N06.20 — Isolated proteinuria with diffuse membranous glomerulonephritis, unspecified
- with diffuse membranous glomerulonephritis N06.29 — Other isolated proteinuria with diffuse membranous glomerulonephritis
- mesangial proliferative (diffuse) N06.3 — Isolated proteinuria with diffuse mesangial proliferative glomerulonephritis
- minimal change N06.0 — Isolated proteinuria with minor glomerular abnormality
- specified pathology NEC N06.8 — Isolated proteinuria with other morphologic lesion
Don't confuse with (Excludes1 for R80.0)
- isolated proteinuria with specific morphological lesion (N06.-)
Common questions about isolated proteinuria ICD-10 codes
What is the ICD-10 code for isolated proteinuria?
- R80.0 — Isolated proteinuria. More specific codes apply when the documentation supports them: N06.9, N06.A, N06.A, N06.6 and others below.
Is R80.0 billable?
- Yes. R80.0 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).
Can R80.0 be used as a principal diagnosis?
- Yes. The Medicare Code Editor doesn't restrict R80.0 as a principal diagnosis.
Is R80.0 a CC or MCC?
- No. R80.0 is neither a CC nor an MCC under MS-DRG v44.0.