ICD-10 code for karyotype abnormal

The ICD-10-CM code for karyotype abnormal is R89.8 (Other abnormal findings in specimens from other organs, systems and tissues).

Within R89, choose R89.8 (Other abnormal findings in specimens from other organs, systems and tissues) only when documentation doesn't support a more specific option: abnormal level of enzymes in specimens from other organs, systems and tissues (R89.0), abnormal level of hormones in specimens from other organs, systems and tissues (R89.1), abnormal level of other drugs, medicaments and biological substances in specimens from other organs, systems and tissues (R89.2), abnormal level of substances chiefly nonmedicinal as to source in specimens from other organs, systems and tissues (R89.3), abnormal immunological findings in specimens from other organs, systems and tissues (R89.4), abnormal microbiological findings in specimens from other organs, systems and tissues (R89.5), abnormal cytological findings in specimens from other organs, systems and tissues (R89.6), abnormal histological findings in specimens from other organs, systems and tissues (R89.7) and 1 more.

It is not a CC or MCC, so as a secondary diagnosis it doesn't change the MS-DRG severity level.

In MS-DRG v44.0, it is part of the grouping logic for DRG 947 (Signs and Symptoms with MCC, relative weight 1.261) and DRG 948 (Signs and Symptoms without MCC, relative weight 0.7835), in MDC 23 (Factors Influencing Health Status and Other Contacts with Health Services), as a principal or secondary diagnosis. The DRG a claim lands in depends on the principal diagnosis, procedures and any CC/MCC secondary diagnoses.