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ICD-10-CM 2027

ICD-10 code for knee pain

M25.569

Pain in unspecified knee

✓ Billable / specific

Confirmed by the official ICD-10-CM index entry “pain (s) › joint › knee”. Page updated September 29, 2026.

About coding knee pain

The ICD-10-CM code for knee pain is M25.569 (Pain in unspecified knee). The official index lists 2 more specific codes, so check the documentation for details such as type, cause, site or severity before settling on M25.569.

Within M25.56, choose M25.569 (unspecified knee) only when documentation doesn't support a more specific option: right knee (M25.561) and left knee (M25.562).

It is not a CC or MCC, so as a secondary diagnosis it doesn't change the MS-DRG severity level.

In MS-DRG v44.0, it is part of the grouping logic for DRG 555 (Signs and Symptoms of Musculoskeletal System and Connective Tissue with MCC, relative weight 1.2913) and DRG 556 (Signs and Symptoms of Musculoskeletal System and Connective Tissue without MCC, relative weight 0.8211), in MDC 08 (Diseases and Disorders of the Musculoskeletal System and Connective Tissue), as a principal or secondary diagnosis. The DRG a claim lands in depends on the principal diagnosis, procedures and any CC/MCC secondary diagnoses.

Related Knee pain codes

Common questions about knee pain ICD-10 codes

What is the ICD-10 code for knee pain?

M25.569 — Pain in unspecified knee. More specific codes apply when the documentation supports them: M25.561, M25.562.

What is the ICD-10 code for pain in right knee?

M25.561 — Pain in right knee.

What is the ICD-10 code for pain in left knee?

M25.562 — Pain in left knee.

Is M25.569 billable?

Yes. M25.569 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).

Can M25.569 be used as a principal diagnosis?

Yes. The Medicare Code Editor doesn't restrict M25.569 as a principal diagnosis.

Is M25.569 a CC or MCC?

No. M25.569 is neither a CC nor an MCC under MS-DRG v44.0.