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ICD-10-CM 2027

ICD-10 code for Leukocytosis

D72.829

Elevated white blood cell count, unspecified

✓ Billable / specific

Confirmed by the official ICD-10-CM index entry “leukocytosis”. Page updated September 29, 2026.

About coding Leukocytosis

The ICD-10-CM code for Leukocytosis is D72.829 (Elevated white blood cell count, unspecified). The official index lists 7 more specific codes, so check the documentation for details such as type, cause, site or severity before settling on D72.829.

It is also searched as elevated white blood cell count, high WBC.

Within D72.82, choose D72.829 (unspecified) only when documentation doesn't support a more specific option: Lymphocytosis (symptomatic) (D72.820), Monocytosis (symptomatic) (D72.821), Plasmacytosis (D72.822), Leukemoid reaction (D72.823), Basophilia (D72.824), Bandemia (D72.825) and other elevated white blood cell count (D72.828).

It is not a CC or MCC, so as a secondary diagnosis it doesn't change the MS-DRG severity level.

In MS-DRG v44.0, it is part of the grouping logic for DRG 814 (Reticuloendothelial and Immunity Disorders with MCC, relative weight 2.0729), DRG 815 (Reticuloendothelial and Immunity Disorders with CC, relative weight 1.0444) and DRG 816 (Reticuloendothelial and Immunity Disorders without CC/MCC, relative weight 0.7381), in MDC 16 (Diseases and Disorders of the Blood and Blood Forming Organs and Immunological Disorders), as a principal or secondary diagnosis. The DRG a claim lands in depends on the principal diagnosis, procedures and any CC/MCC secondary diagnoses.

Related Leukocytosis codes

Common questions about Leukocytosis ICD-10 codes

What is the ICD-10 code for Leukocytosis?

D72.829 — Elevated white blood cell count, unspecified. More specific codes apply when the documentation supports them: D72.820, D72.821, D72.822, D72.823 and others below.

What is the ICD-10 code for lymphocytosis (symptomatic)?

D72.820 — Lymphocytosis (symptomatic).

What is the ICD-10 code for monocytosis (symptomatic)?

D72.821 — Monocytosis (symptomatic).

What is the ICD-10 code for plasmacytosis?

D72.822 — Plasmacytosis.

What is the ICD-10 code for leukemoid reaction?

D72.823 — Leukemoid reaction.

What is the ICD-10 code for basophilia?

D72.824 — Basophilia.

What is the ICD-10 code for bandemia?

D72.825 — Bandemia.

Is D72.829 billable?

Yes. D72.829 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).

Can D72.829 be used as a principal diagnosis?

Yes. The Medicare Code Editor doesn't restrict D72.829 as a principal diagnosis.

Is D72.829 a CC or MCC?

No. D72.829 is neither a CC nor an MCC under MS-DRG v44.0.