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ICD-10-CM 2027

ICD-10 code for liver hypertrophy

R16.0

Hepatomegaly, not elsewhere classified

✓ Billable / specific

From the official ICD-10-CM alphabetic index entry “Hypertrophy, hypertrophic › liver”. Page updated September 29, 2026.

About coding liver hypertrophy

The ICD-10-CM code for liver hypertrophy is R16.0 (Hepatomegaly, not elsewhere classified). The official index lists 2 more specific codes, so check the documentation for details such as type, cause, site or severity before settling on R16.0.

Within R16 (Hepatomegaly and splenomegaly, not elsewhere classified), R16.0 is specifically for Hepatomegaly, not elsewhere classified. Related codes cover splenomegaly, not elsewhere classified (R16.1) and Hepatomegaly with splenomegaly, not elsewhere classified (R16.2).

It is not a CC or MCC, so as a secondary diagnosis it doesn't change the MS-DRG severity level.

In MS-DRG v44.0, it is part of the grouping logic for DRG 441 (Disorders of Liver Except Malignancy, Cirrhosis or Alcoholic Hepatitis with MCC, relative weight 1.8219), DRG 442 (Disorders of Liver Except Malignancy, Cirrhosis or Alcoholic Hepatitis with CC, relative weight 0.9602) and DRG 443 (Disorders of Liver Except Malignancy, Cirrhosis or Alcoholic Hepatitis without CC/MCC, relative weight 0.6885), in MDC 07 (Diseases and Disorders of the Hepatobiliary System and Pancreas), as a principal or secondary diagnosis. The DRG a claim lands in depends on the principal diagnosis, procedures and any CC/MCC secondary diagnoses.

More specific liver hypertrophy codes (official index)

  • acute K76.89 — Other specified diseases of liver
  • congenital Q44.79 — Other congenital malformations of liver
  • cirrhotic
  • fatty

Common questions about liver hypertrophy ICD-10 codes

What is the ICD-10 code for liver hypertrophy?

R16.0 — Hepatomegaly, not elsewhere classified. More specific codes apply when the documentation supports them: K76.89, Q44.79.

What is the ICD-10 code for acute liver hypertrophy?

K76.89 — Other specified diseases of liver.

What is the ICD-10 code for congenital liver hypertrophy?

Q44.79 — Other congenital malformations of liver.

Is R16.0 billable?

Yes. R16.0 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).

Can R16.0 be used as a principal diagnosis?

Yes. The Medicare Code Editor doesn't restrict R16.0 as a principal diagnosis.

Is R16.0 a CC or MCC?

No. R16.0 is neither a CC nor an MCC under MS-DRG v44.0.