ICD-10-CM 2027
ICD-10 code for Loneliness
From the official ICD-10-CM alphabetic index entry “Loneliness”. Page updated September 29, 2026.
About coding Loneliness
The ICD-10-CM code for Loneliness is R45.89 (Other symptoms and signs involving emotional state).
Within R45.8, choose R45.89 (Other symptoms and signs involving emotional state) only when documentation doesn't support a more specific option: low self-esteem (R45.81), Worries (R45.82), excessive crying of child, adolescent or adult (R45.83), Anhedonia (R45.84), Homicidal and suicidal ideations (R45.85), emotional lability (R45.86), Impulsiveness (R45.87) and nonsuicidal self-harm (R45.88).
It is not a CC or MCC, so as a secondary diagnosis it doesn't change the MS-DRG severity level.
In MS-DRG v44.0, it is part of the grouping logic for DRG 880 (Acute Adjustment Reaction and Psychosocial Dysfunction, relative weight 0.9306), in MDC 19 (Mental Diseases and Disorders), as a principal or secondary diagnosis. The DRG a claim lands in depends on the principal diagnosis, procedures and any CC/MCC secondary diagnoses.
Common questions about Loneliness ICD-10 codes
What is the ICD-10 code for Loneliness?
- R45.89 — Other symptoms and signs involving emotional state.
Is R45.89 billable?
- Yes. R45.89 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).
Can R45.89 be used as a principal diagnosis?
- Yes. The Medicare Code Editor doesn't restrict R45.89 as a principal diagnosis.
Is R45.89 a CC or MCC?
- No. R45.89 is neither a CC nor an MCC under MS-DRG v44.0.