ICD-10-CM 2027
ICD-10 code for Long-term drug therapy
Choose a code from the options below based on the documentation.
From the official ICD-10-CM alphabetic index entry “Long-term (current) (prophylactic) drug therapy (use of)”. Page updated September 29, 2026.
About coding Long-term drug therapy
The official ICD-10-CM index doesn't give a single default code for long-term drug therapy; the code depends on the details below.
More specific Long-term drug therapy codes (official index)
- 5-fluorouracil Z79.631 — Long term (current) use of antimetabolite agent
- 6-mercaptopurine Z79.631 — Long term (current) use of antimetabolite agent
- adalimumab Z79.620 — Long term (current) use of immunosuppressive biologic
- agents affecting estrogen receptors and estrogen levels NEC Z79.818 — Long term (current) use of other agents affecting estrogen receptors and estrogen levels
- alkylating agent Z79.630 — Long term (current) use of alkylating agent
- anastrozole (Arimidex) Z79.811 — Long term (current) use of aromatase inhibitors
- antibiotics Z79.2 — Long term (current) use of antibiotics
- short-term use - omit code
- anticoagulants Z79.01 — Long term (current) use of anticoagulants
- antidiabetic drugs, injectable, non-insulin Z79.85 — Long-term (current) use of injectable non-insulin antidiabetic drugs
- anti-inflammatory, non-steroidal (NSAID) Z79.1 — Long term (current) use of non-steroidal anti-inflammatories (NSAID)
- antimetabolite agent Z79.631 — Long term (current) use of antimetabolite agent
- antiplatelet Z79.02 — Long term (current) use of antithrombotics/antiplatelets
- antithrombotics Z79.02 — Long term (current) use of antithrombotics/antiplatelets
- antitumor antibiotic Z79.632 — Long term (current) use of antitumor antibiotic
- apremilast Z79.61 — Long term (current) use of immunomodulator
- aromatase inhibitors Z79.811 — Long term (current) use of aromatase inhibitors
- aspirin Z79.82 — Long term (current) use of aspirin
- azathioprine Z79.624 — Long term (current) use of inhibitors of nucleotide synthesis
- birth control pill or patch Z79.3 — Long term (current) use of hormonal contraceptives
- bisphosphonates Z79.83 — Long term (current) use of bisphosphonates
- bleomycin Z79.632 — Long term (current) use of antitumor antibiotic
- calcineurin inhibitor Z79.621 — Long term (current) use of calcineurin inhibitor
- chlorambucil Z79.630 — Long term (current) use of alkylating agent
- cisplatin Z79.630 — Long term (current) use of alkylating agent
- contraceptive, oral Z79.3 — Long term (current) use of hormonal contraceptives
- cyclophosphamide Z79.630 — Long term (current) use of alkylating agent
- cyclosporine Z79.621 — Long term (current) use of calcineurin inhibitor
- cytarabine Z79.631 — Long term (current) use of antimetabolite agent
- doxorubicin Z79.632 — Long term (current) use of antitumor antibiotic
- drug, specified NEC Z79.899 — Other long term (current) drug therapy
- estrogen receptor downregulators Z79.818 — Long term (current) use of other agents affecting estrogen receptors and estrogen levels
- etanercept Z79.620 — Long term (current) use of immunosuppressive biologic
- etoposide Z79.634 — Long term (current) use of topoisomerase inhibitor
- Evista Z79.810 — Long term (current) use of selective estrogen receptor modulators (SERMs)
- exemestane (Aromasin) Z79.811 — Long term (current) use of aromatase inhibitors
- Fareston Z79.810 — Long term (current) use of selective estrogen receptor modulators (SERMs)
- fulvestrant (Faslodex) Z79.818 — Long term (current) use of other agents affecting estrogen receptors and estrogen levels
- gonadotropin-releasing hormone (GnRH) agonist Z79.818 — Long term (current) use of other agents affecting estrogen receptors and estrogen levels
- goserelin acetate (Zoladex) Z79.818 — Long term (current) use of other agents affecting estrogen receptors and estrogen levels
- hormone replacement Z79.890 — Hormone replacement therapy
- hydroxyurea Z79.64 — Long term (current) use of myelosuppressive agent
- immunomodulators, unspecified Z79.60 — Long term (current) use of unspecified immunomodulators and immunosuppressants
- specified NEC Z79.69 — Long term (current) use of other immunomodulators and immunosuppressants
- immunomodulatory imide drug Z79.61 — Long term (current) use of immunomodulator
- immunosuppressants, unspecified Z79.60 — Long term (current) use of unspecified immunomodulators and immunosuppressants
- specified NEC Z79.69 — Long term (current) use of other immunomodulators and immunosuppressants
- immunosuppressive biologic Z79.620 — Long term (current) use of immunosuppressive biologic
- infliximab Z79.620 — Long term (current) use of immunosuppressive biologic
- inhibitors of nucleotide synthesis Z79.624 — Long term (current) use of inhibitors of nucleotide synthesis
- insulin Z79.4 — Long term (current) use of insulin
- irinotecan Z79.634 — Long term (current) use of topoisomerase inhibitor
- Janus kinase inhibitor Z79.622 — Long term (current) use of Janus kinase inhibitor
- lenalidomide Z79.61 — Long term (current) use of immunomodulator
- letrozole (Femara) Z79.811 — Long term (current) use of aromatase inhibitors
- leuprolide acetate (leuprorelin) (Lupron) Z79.818 — Long term (current) use of other agents affecting estrogen receptors and estrogen levels
- mammalian target of rapamycin (mTOR) inhibitor Z79.623 — Long term (current) use of mammalian target of rapamycin (mTOR) inhibitor
- megestrol acetate (Megace) Z79.818 — Long term (current) use of other agents affecting estrogen receptors and estrogen levels
- methadone for pain management Z79.891 — Long term (current) use of opiate analgesic
- mitomycin C Z79.632 — Long term (current) use of antitumor antibiotic
- mitotic inhibitor Z79.633 — Long term (current) use of mitotic inhibitor
- monoclonal antibodies Z79.620 — Long term (current) use of immunosuppressive biologic
- mycophenolate Z79.624 — Long term (current) use of inhibitors of nucleotide synthesis
- myelosuppressive agent Z79.64 — Long term (current) use of myelosuppressive agent
- Nolvadex Z79.810 — Long term (current) use of selective estrogen receptor modulators (SERMs)
- non-insulin antidiabetic drug, injectable Z79.85 — Long-term (current) use of injectable non-insulin antidiabetic drugs
- non-steroidal anti-inflammatories (NSAID) Z79.1 — Long term (current) use of non-steroidal anti-inflammatories (NSAID)
- opiate analgesic Z79.891 — Long term (current) use of opiate analgesic
- oral
- antidiabetic Z79.84 — Long term (current) use of oral hypoglycemic drugs
- contraceptive Z79.3 — Long term (current) use of hormonal contraceptives
- hypoglycemic Z79.84 — Long term (current) use of oral hypoglycemic drugs
- paclitaxel Z79.633 — Long term (current) use of mitotic inhibitor
- plant alkaloids Z79.633 — Long term (current) use of mitotic inhibitor
- pomalidomide Z79.61 — Long term (current) use of immunomodulator
- purine synthesis (IMDH) inhibitors Z79.624 — Long term (current) use of inhibitors of nucleotide synthesis
- raloxifene (Evista) Z79.810 — Long term (current) use of selective estrogen receptor modulators (SERMs)
- selective estrogen receptor modulators (SERMs) Z79.810 — Long term (current) use of selective estrogen receptor modulators (SERMs)
- sirolimus Z79.623 — Long term (current) use of mammalian target of rapamycin (mTOR) inhibitor
- steroids
- inhaled Z79.51 — Long term (current) use of inhaled steroids
- systemic Z79.52 — Long term (current) use of systemic steroids
- tacrolimus Z79.621 — Long term (current) use of calcineurin inhibitor
- tamoxifen (Nolvadex) Z79.810 — Long term (current) use of selective estrogen receptor modulators (SERMs)
- tofacitinib Z79.622 — Long term (current) use of Janus kinase inhibitor
- topoisomerase inhibitor Z79.634 — Long term (current) use of topoisomerase inhibitor
- topotecan Z79.634 — Long term (current) use of topoisomerase inhibitor
- toremifene (Fareston) Z79.810 — Long term (current) use of selective estrogen receptor modulators (SERMs)
- vinblastine Z79.633 — Long term (current) use of mitotic inhibitor
- vincristine Z79.633 — Long term (current) use of mitotic inhibitor
Common questions about Long-term drug therapy ICD-10 codes
What is the ICD-10 code for 5-fluorouracil long-term drug therapy?
- Z79.631 — Long term (current) use of antimetabolite agent.
What is the ICD-10 code for 6-mercaptopurine long-term drug therapy?
- Z79.631 — Long term (current) use of antimetabolite agent.
What is the ICD-10 code for adalimumab long-term drug therapy?
- Z79.620 — Long term (current) use of immunosuppressive biologic.
What is the ICD-10 code for alkylating agent long-term drug therapy?
- Z79.630 — Long term (current) use of alkylating agent.
What is the ICD-10 code for anastrozole long-term drug therapy?
- Z79.811 — Long term (current) use of aromatase inhibitors.
What is the ICD-10 code for antibiotics long-term drug therapy?
- Z79.2 — Long term (current) use of antibiotics.
What is the ICD-10 code for anticoagulants long-term drug therapy?
- Z79.01 — Long term (current) use of anticoagulants.