ICD-10-CM 2027
ICD-10 code for LSD reaction
From the official ICD-10-CM alphabetic index entry “LSD reaction (acute) (without dependence)”. Page updated September 29, 2026.
About coding LSD reaction
The ICD-10-CM code for LSD reaction is F16.90 (Hallucinogen use, unspecified, uncomplicated). The official index lists 1 more specific code, so check the documentation for details such as type, cause, site or severity before settling on F16.90.
Within F16.9 (hallucinogen use, unspecified), F16.90 is specifically for hallucinogen use, unspecified, uncomplicated. Related codes cover in remission (F16.91), with intoxication (F16.92), with hallucinogen-induced mood disorder (F16.94), with hallucinogen-induced psychotic disorder (F16.95), with other specified hallucinogen-induced disorder (F16.98) and with unspecified hallucinogen-induced disorder (F16.99).
It is not a CC or MCC, so as a secondary diagnosis it doesn't change the MS-DRG severity level.
In MS-DRG v44.0, it is part of the grouping logic for DRG 894 (Alcohol, Drug Abuse or Dependence, Left AMA, relative weight 0.6275), DRG 895 (Alcohol, Drug Abuse or Dependence with Rehabilitation Therapy, relative weight 1.4266), DRG 896 (Alcohol, Drug Abuse or Dependence without Rehabilitation Therapy with MCC, relative weight 1.6617) and DRG 897 (Alcohol, Drug Abuse or Dependence without Rehabilitation Therapy without MCC, relative weight 0.8584), in MDC 20 (Alcohol/Drug Use and Alcohol/Drug Induced Organic Mental Disorders), as a principal or secondary diagnosis. The DRG a claim lands in depends on the principal diagnosis, procedures and any CC/MCC secondary diagnoses.
More specific LSD reaction codes (official index)
- with dependence F16.20 — Hallucinogen dependence, uncomplicated
Common questions about LSD reaction ICD-10 codes
What is the ICD-10 code for LSD reaction?
- F16.90 — Hallucinogen use, unspecified, uncomplicated. More specific codes apply when the documentation supports them: F16.20.
Is F16.90 billable?
- Yes. F16.90 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).
Can F16.90 be used as a principal diagnosis?
- Yes. The Medicare Code Editor doesn't restrict F16.90 as a principal diagnosis.
Is F16.90 a CC or MCC?
- No. F16.90 is neither a CC nor an MCC under MS-DRG v44.0.