ICD-10-CM 2027
ICD-10 code for Melanosis
From the official ICD-10-CM alphabetic index entry “Melanosis”. Page updated September 29, 2026.
About coding Melanosis
The ICD-10-CM code for Melanosis is L81.4 (Other melanin hyperpigmentation). The official index lists 16 more specific codes, so check the documentation for details such as type, cause, site or severity before settling on L81.4.
Within L81, choose L81.4 (Other melanin hyperpigmentation) only when documentation doesn't support a more specific option: postinflammatory hyperpigmentation (L81.0), Chloasma (L81.1), Freckles (L81.2), cafe au lait spots (L81.3), Leukoderma, not elsewhere classified (L81.5), other disorders of diminished melanin formation (L81.6), pigmented purpuric dermatosis (L81.7), other specified disorders of pigmentation (L81.8) and 1 more.
It is not a CC or MCC, so as a secondary diagnosis it doesn't change the MS-DRG severity level.
In MS-DRG v44.0, it is part of the grouping logic for DRG 606 (Minor Skin Disorders with MCC, relative weight 1.5728), DRG 607 (Minor Skin Disorders without MCC, relative weight 0.8772) and DRG 795 (Normal Newborn, relative weight 0.2022), in MDC 09 (Diseases and Disorders of the Skin, Subcutaneous Tissue and Breast) and MDC 15 (Newborns and Other Neonates with Conditions Originating in the Perinatal Period), as a principal or secondary diagnosis. The DRG a claim lands in depends on the principal diagnosis, procedures and any CC/MCC secondary diagnoses.
More specific Melanosis codes (official index)
- addisonian E27.1 — Primary adrenocortical insufficiency
- tuberculous A18.7 — Tuberculosis of adrenal glands
- adrenal E27.1 — Primary adrenocortical insufficiency
- colon K63.89 — Other specified diseases of intestine
- conjunctiva
- congenital Q13.89 — Other congenital malformations of anterior segment of eye
- cornea (presenile) (senile)
- congenital Q13.4 — Other congenital corneal malformations
- eye NEC H57.89 — Other specified disorders of eye and adnexa
- congenital Q15.8 — Other specified congenital malformations of eye
- lenticularis progressiva Q82.1 — Xeroderma pigmentosum
- liver K76.89 — Other specified diseases of liver
- precancerous
- malignant melanoma in
- Riehl's L81.4 — Other melanin hyperpigmentation
- sclera H15.89 — Other disorders of sclera
- congenital Q13.89 — Other congenital malformations of anterior segment of eye
- suprarenal E27.1 — Primary adrenocortical insufficiency
- tar L81.4 — Other melanin hyperpigmentation
- toxic L81.4 — Other melanin hyperpigmentation
Common questions about Melanosis ICD-10 codes
What is the ICD-10 code for Melanosis?
- L81.4 — Other melanin hyperpigmentation. More specific codes apply when the documentation supports them: E27.1, A18.7, E27.1, K63.89 and others below.
What is the ICD-10 code for addisonian melanosis?
- E27.1 — Primary adrenocortical insufficiency.
What is the ICD-10 code for adrenal melanosis?
- E27.1 — Primary adrenocortical insufficiency.
What is the ICD-10 code for colon melanosis?
- K63.89 — Other specified diseases of intestine.
What is the ICD-10 code for eye nec melanosis?
- H57.89 — Other specified disorders of eye and adnexa.
What is the ICD-10 code for lenticularis progressiva melanosis?
- Q82.1 — Xeroderma pigmentosum.
What is the ICD-10 code for liver melanosis?
- K76.89 — Other specified diseases of liver.
Is L81.4 billable?
- Yes. L81.4 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).
Can L81.4 be used as a principal diagnosis?
- Yes. The Medicare Code Editor doesn't restrict L81.4 as a principal diagnosis.
Is L81.4 a CC or MCC?
- No. L81.4 is neither a CC nor an MCC under MS-DRG v44.0.