ICD-10-CM 2027
ICD-10 code for multiple sites osteolysis
From the official ICD-10-CM alphabetic index entry “Osteolysis › multiple sites”. Page updated September 29, 2026.
About coding multiple sites osteolysis
The ICD-10-CM code for multiple sites osteolysis is M89.59 (Osteolysis, multiple sites).
Within M89.5 (osteolysis), M89.59 is specifically for osteolysis, multiple sites. Related codes cover unspecified site (M89.50), shoulder (M89.51), upper arm (M89.52), forearm (M89.53), hand (M89.54), thigh (M89.55), lower leg (M89.56), ankle and foot (M89.57) and 1 more.
It is not a CC or MCC, so as a secondary diagnosis it doesn't change the MS-DRG severity level.
In MS-DRG v44.0, it is part of the grouping logic for DRG 564 (Other Musculoskeletal System and Connective Tissue Diagnoses with MCC, relative weight 1.4908), DRG 565 (Other Musculoskeletal System and Connective Tissue Diagnoses with CC, relative weight 0.9783) and DRG 566 (Other Musculoskeletal System and Connective Tissue Diagnoses without CC/MCC, relative weight 0.7378), in MDC 08 (Diseases and Disorders of the Musculoskeletal System and Connective Tissue), as a principal or secondary diagnosis. The DRG a claim lands in depends on the principal diagnosis, procedures and any CC/MCC secondary diagnoses.
Common questions about multiple sites osteolysis ICD-10 codes
What is the ICD-10 code for multiple sites osteolysis?
- M89.59 — Osteolysis, multiple sites.
Is M89.59 billable?
- Yes. M89.59 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).
Can M89.59 be used as a principal diagnosis?
- Yes. The Medicare Code Editor doesn't restrict M89.59 as a principal diagnosis.
Is M89.59 a CC or MCC?
- No. M89.59 is neither a CC nor an MCC under MS-DRG v44.0.