ICD-10-CM 2027
ICD-10 code for neonatal encephalopathy
From the official ICD-10-CM alphabetic index entry “Encephalopathy (acute) › neonatal”. Page updated September 29, 2026.
About coding neonatal encephalopathy
The ICD-10-CM code for neonatal encephalopathy is P91.819 (Neonatal encephalopathy, unspecified). The official index lists 1 more specific code, so check the documentation for details such as type, cause, site or severity before settling on P91.819.
Within P91.81, choose P91.819 (unspecified) only when documentation doesn't support a more specific option: in diseases classified elsewhere (P91.811).
It is not a CC or MCC, so as a secondary diagnosis it doesn't change the MS-DRG severity level.
In MS-DRG v44.0, it is part of the grouping logic for DRG 791 (Prematurity with Major Problems, relative weight 4.1075) and DRG 793 (Full Term Neonate with Major Problems, relative weight 4.2195), in MDC 15 (Newborns and Other Neonates with Conditions Originating in the Perinatal Period), as a principal or secondary diagnosis. The DRG a claim lands in depends on the principal diagnosis, procedures and any CC/MCC secondary diagnoses.
More specific neonatal encephalopathy codes (official index)
- in diseases classified elsewhere P91.811 — Neonatal encephalopathy in diseases classified elsewhere
Common questions about neonatal encephalopathy ICD-10 codes
What is the ICD-10 code for neonatal encephalopathy?
- P91.819 — Neonatal encephalopathy, unspecified. More specific codes apply when the documentation supports them: P91.811.
Is P91.819 billable?
- Yes. P91.819 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).
Can P91.819 be used as a principal diagnosis?
- Yes. The Medicare Code Editor doesn't restrict P91.819 as a principal diagnosis.
Is P91.819 a CC or MCC?
- No. P91.819 is neither a CC nor an MCC under MS-DRG v44.0.