ICD-10-CM 2027
ICD-10 code for opiate analgesic long-term drug therapy
From the official ICD-10-CM alphabetic index entry “Long-term (current) (prophylactic) drug therapy (use of) › opiate analgesic”. Page updated September 29, 2026.
About coding opiate analgesic long-term drug therapy
The ICD-10-CM code for opiate analgesic long-term drug therapy is Z79.891 (Long term (current) use of opiate analgesic).
Within Z79.89 (other long term (current) drug therapy), Z79.891 is specifically for long term (current) use of opiate analgesic. Related codes cover hormone replacement therapy (Z79.890) and other long term (current) drug therapy (Z79.899).
The conditions in its Excludes2 note aren't part of Z79.891, but may be coded alongside it if the patient has both: methadone use NOS (F11.9-) and use of methadone for treatment of heroin addiction (F11.2-).
It is not a CC or MCC, so as a secondary diagnosis it doesn't change the MS-DRG severity level.
Common questions about opiate analgesic long-term drug therapy ICD-10 codes
What is the ICD-10 code for opiate analgesic long-term drug therapy?
- Z79.891 — Long term (current) use of opiate analgesic.
Is Z79.891 billable?
- Yes. Z79.891 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).
Can Z79.891 be used as a principal diagnosis?
- Yes. The Medicare Code Editor doesn't restrict Z79.891 as a principal diagnosis.
Is Z79.891 a CC or MCC?
- No. Z79.891 is neither a CC nor an MCC under MS-DRG v44.0.