ICD-10-CM 2027
ICD-10 code for pancytopenia
From the official ICD-10-CM alphabetic index entry “Pancytopenia (acquired)”. Page updated September 29, 2026.
About coding pancytopenia
The ICD-10-CM code for pancytopenia is D61.818 (Other pancytopenia). The official index lists 5 more specific codes, so check the documentation for details such as type, cause, site or severity before settling on D61.818.
Within D61.81, choose D61.818 (Other pancytopenia) only when documentation doesn't support a more specific option: antineoplastic chemotherapy induced pancytopenia (D61.810) and other drug-induced pancytopenia (D61.811).
As a secondary diagnosis it is a CC (complication or comorbidity), which can move an inpatient stay into the "with CC" MS-DRG of its family, unless the principal diagnosis excludes it.
In MS-DRG v44.0, it is part of the grouping logic for DRG 808 (Major Hematological and Immunological Diagnoses Except Sickle Cell Crisis and Coagulation Disorders with MCC, relative weight 2.1705), DRG 809 (Major Hematological and Immunological Diagnoses Except Sickle Cell Crisis and Coagulation Disorders with CC, relative weight 1.2262) and DRG 810 (Major Hematological and Immunological Diagnoses Except Sickle Cell Crisis and Coagulation Disorders without CC/MCC, relative weight 1.075), in MDC 16 (Diseases and Disorders of the Blood and Blood Forming Organs and Immunological Disorders), as a principal or secondary diagnosis. The DRG a claim lands in depends on the principal diagnosis, procedures and any CC/MCC secondary diagnoses.
More specific pancytopenia codes (official index)
- with
- malformations D61.09 — Other constitutional aplastic anemia
- myelodysplastic syndrome
- antineoplastic chemotherapy induced D61.810 — Antineoplastic chemotherapy induced pancytopenia
- congenital D61.09 — Other constitutional aplastic anemia
- drug-induced NEC D61.811 — Other drug-induced pancytopenia
- Fanconi D61.03 — Fanconi anemia
Common questions about pancytopenia ICD-10 codes
What is the ICD-10 code for pancytopenia?
- D61.818 — Other pancytopenia. More specific codes apply when the documentation supports them: D61.09, D61.810, D61.09, D61.811 and others below.
What is the ICD-10 code for antineoplastic chemotherapy induced pancytopenia?
- D61.810 — Antineoplastic chemotherapy induced pancytopenia.
What is the ICD-10 code for congenital pancytopenia?
- D61.09 — Other constitutional aplastic anemia.
What is the ICD-10 code for drug-induced nec pancytopenia?
- D61.811 — Other drug-induced pancytopenia.
What is the ICD-10 code for fanconi pancytopenia?
- D61.03 — Fanconi anemia.
Is D61.818 billable?
- Yes. D61.818 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).
Can D61.818 be used as a principal diagnosis?
- Yes. The Medicare Code Editor doesn't restrict D61.818 as a principal diagnosis.
Is D61.818 a CC or MCC?
- D61.818 is a CC (complication or comorbidity) under MS-DRG v44.0, unless excluded by the principal diagnosis.