ICD-10-CM 2027
ICD-10 code for plasma cell leukemia
From the official ICD-10-CM alphabetic index entry “Leukemia, leukemic › plasma cell”. Page updated September 29, 2026.
About coding plasma cell leukemia
The ICD-10-CM code for plasma cell leukemia is C90.1 (Plasma cell leukemia).
Within C90 (multiple myeloma and malignant plasma cell neoplasms), C90.1 is specifically for plasma cell leukemia. Related codes cover multiple myeloma (C90.0), Extramedullary plasmacytoma (C90.2) and Solitary plasmacytoma (C90.3).
To report this condition, pick the subcode that matches the documentation: C90.10 (not having achieved remission), C90.11 (in remission) and C90.12 (in relapse).
It has been part of ICD-10-CM since the code set took effect on October 1, 2015 and hasn't changed since.