ICD-10-CM 2027
ICD-10 code for postpartum depression
Confirmed by the official ICD-10-CM index entry “depression (acute) (mental) › postpartum (nos)”. Page updated September 29, 2026.
About coding postpartum depression
The ICD-10-CM code for postpartum depression is F53.0 (Postpartum depression). The official index lists 1 more specific code, so check the documentation for details such as type, cause, site or severity before settling on F53.0.
Within F53 (mental and behavioral disorders associated with the puerperium, not elsewhere classified), F53.0 is specifically for postpartum depression. Related codes cover puerperal psychosis (F53.1).
It is not a CC or MCC, so as a secondary diagnosis it doesn't change the MS-DRG severity level.
In MS-DRG v44.0, it is part of the grouping logic for DRG 881 (Depressive Neuroses, relative weight 0.895), in MDC 19 (Mental Diseases and Disorders), as a principal or secondary diagnosis. The DRG a claim lands in depends on the principal diagnosis, procedures and any CC/MCC secondary diagnoses.
Related Postpartum depression codes
- F53.1 Puerperal psychosis
Common questions about postpartum depression ICD-10 codes
What is the ICD-10 code for postpartum depression?
- F53.0 — Postpartum depression. More specific codes apply when the documentation supports them: F53.1.
What is the ICD-10 code for puerperal psychosis?
- F53.1 — Puerperal psychosis.
Is F53.0 billable?
- Yes. F53.0 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).
Can F53.0 be used as a principal diagnosis?
- Yes. The Medicare Code Editor doesn't restrict F53.0 as a principal diagnosis.
Is F53.0 a CC or MCC?
- No. F53.0 is neither a CC nor an MCC under MS-DRG v44.0.