ICD-10-CM 2027
ICD-10 code for prematurity apnea
From the official ICD-10-CM alphabetic index entry “Apnea, apneic (of) (spells) › prematurity”. Page updated September 29, 2026.
About coding prematurity apnea
The ICD-10-CM code for prematurity apnea is P28.49 (Other apnea of newborn).
Within P28.4, choose P28.49 (Other apnea of newborn) only when documentation doesn't support a more specific option: unspecified apnea of newborn (P28.40), central neonatal apnea of newborn (P28.41), obstructive apnea of newborn (P28.42) and mixed neonatal apnea of newborn (P28.43).
As a secondary diagnosis it is a CC (complication or comorbidity), which can move an inpatient stay into the "with CC" MS-DRG of its family, unless the principal diagnosis excludes it.
In MS-DRG v44.0, it is part of the grouping logic for DRG 794 (Neonate with Other Significant Problems, relative weight 1.4935), in MDC 15 (Newborns and Other Neonates with Conditions Originating in the Perinatal Period), as a principal or secondary diagnosis. The DRG a claim lands in depends on the principal diagnosis, procedures and any CC/MCC secondary diagnoses.
Common questions about prematurity apnea ICD-10 codes
What is the ICD-10 code for prematurity apnea?
- P28.49 — Other apnea of newborn.
Is P28.49 billable?
- Yes. P28.49 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).
Can P28.49 be used as a principal diagnosis?
- Yes. The Medicare Code Editor doesn't restrict P28.49 as a principal diagnosis.
Is P28.49 a CC or MCC?
- P28.49 is a CC (complication or comorbidity) under MS-DRG v44.0, unless excluded by the principal diagnosis.