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ICD-10-CM 2027

ICD-10 code for prophylactic

Choose a code from the options below based on the documentation.

From the official ICD-10-CM alphabetic index entry “Prophylactic”. Page updated September 29, 2026.

About coding prophylactic

The official ICD-10-CM index doesn't give a single default code for prophylactic; the code depends on the details below.

More specific prophylactic codes (official index)

  • administration of
  • antibiotics, long-term Z79.2 — Long term (current) use of antibiotics
  • short-term use - omit code
  • drug Z79.899 — Other long term (current) drug therapy
  • medication Z79.899 — Other long term (current) drug therapy
  • organ removal (for neoplasia management) Z40.00 — Encounter for prophylactic removal of unspecified organ
  • breast Z40.01 — Encounter for prophylactic removal of breast
  • fallopian tube (s) Z40.03 — Encounter for prophylactic removal of fallopian tube(s)
  • with ovary (s) Z40.02 — Encounter for prophylactic removal of ovary(s)
  • ovary (s) Z40.02 — Encounter for prophylactic removal of ovary(s)
  • specified site NEC Z40.09 — Encounter for prophylactic removal of other organ
  • surgery Z40.9 — Encounter for prophylactic surgery, unspecified
  • for risk factors related to malignant neoplasm
  • specified NEC Z40.89 — Encounter for other prophylactic surgery
  • vaccination Z23 — Encounter for immunization

Common questions about prophylactic ICD-10 codes

What is the ICD-10 code for medication prophylactic?

Z79.899 — Other long term (current) drug therapy.

What is the ICD-10 code for organ removal prophylactic?

Z40.00 — Encounter for prophylactic removal of unspecified organ.

What is the ICD-10 code for surgery prophylactic?

Z40.9 — Encounter for prophylactic surgery, unspecified.

What is the ICD-10 code for vaccination prophylactic?

Z23 — Encounter for immunization.