ICD-10-CM 2027
ICD-10 code for prostate cancer
Confirmed by the official ICD-10-CM index entry “neoplasms|neoplasm, neoplastic › prostate (gland)|malignant primary”. Page updated September 29, 2026.
About coding prostate cancer
The ICD-10-CM code for prostate cancer is C61 (Malignant neoplasm of prostate). The official index lists 1 more specific code, so check the documentation for details such as type, cause, site or severity before settling on C61.
Don't report C61 together with the conditions in its Excludes1 note: malignant neoplasm of seminal vesicle (C63.7).
Use an additional code, if applicable, to identify: hormone sensitivity status (Z19.1-Z19.2) and rising PSA following treatment for malignant neoplasm of prostate (R97.21).
It is not a CC or MCC, so as a secondary diagnosis it doesn't change the MS-DRG severity level.
Related Prostate cancer codes
- R97.21 Rising PSA following treatment for malignant neoplasm of prostate
Don't confuse with (Excludes1 for C61)
- malignant neoplasm of seminal vesicle (C63.7)
Common questions about prostate cancer ICD-10 codes
What is the ICD-10 code for prostate cancer?
- C61 — Malignant neoplasm of prostate. More specific codes apply when the documentation supports them: R97.21.
What is the ICD-10 code for rising psa following treatment for malignant neoplasm of prostate?
- R97.21 — Rising PSA following treatment for malignant neoplasm of prostate.
Is C61 billable?
- Yes. C61 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).
Can C61 be used as a principal diagnosis?
- Yes. The Medicare Code Editor doesn't restrict C61 as a principal diagnosis.
Is C61 a CC or MCC?
- No. C61 is neither a CC nor an MCC under MS-DRG v44.0.