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ICD-10-CM 2027

ICD-10 code for secondary neutropenia

D70.4

Cyclic neutropenia

✓ Billable / specific

From the official ICD-10-CM alphabetic index entry “Neutropenia, neutropenic (chronic) (genetic) (idiopathic) (immune) (infantile) (malignant) (pernicious) (splenic) › secondary (cyclic) (periodic) (splenic)”. Page updated September 29, 2026.

About coding secondary neutropenia

The ICD-10-CM code for secondary neutropenia is D70.4 (Cyclic neutropenia). The official index lists 2 more specific codes, so check the documentation for details such as type, cause, site or severity before settling on D70.4.

Within D70 (neutropenia), D70.4 is specifically for Cyclic neutropenia. Related codes cover congenital agranulocytosis (D70.0), agranulocytosis secondary to cancer chemotherapy (D70.1), other drug-induced agranulocytosis (D70.2), due to infection (D70.3), other neutropenia (D70.8) and unspecified (D70.9).

Use an additional code for any associated: fever (R50.81).

It is not a CC or MCC, so as a secondary diagnosis it doesn't change the MS-DRG severity level.

More specific secondary neutropenia codes (official index)

  • drug-induced D70.2 — Other drug-induced agranulocytosis
  • due to cytoreductive cancer chemotherapy D70.1 — Agranulocytosis secondary to cancer chemotherapy

Common questions about secondary neutropenia ICD-10 codes

What is the ICD-10 code for secondary neutropenia?

D70.4 — Cyclic neutropenia. More specific codes apply when the documentation supports them: D70.2, D70.1.

What is the ICD-10 code for drug-induced secondary neutropenia?

D70.2 — Other drug-induced agranulocytosis.

Is D70.4 billable?

Yes. D70.4 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).

Can D70.4 be used as a principal diagnosis?

Yes. The Medicare Code Editor doesn't restrict D70.4 as a principal diagnosis.

Is D70.4 a CC or MCC?

No. D70.4 is neither a CC nor an MCC under MS-DRG v44.0.