ICD-10-CM 2027
ICD-10 code for simplex herpes
From the official ICD-10-CM alphabetic index entry “Herpes, herpesvirus, herpetic › simplex”. Page updated September 29, 2026.
About coding simplex herpes
The ICD-10-CM code for simplex herpes is B00.9 (Herpesviral infection, unspecified). The official index lists 10 more specific codes, so check the documentation for details such as type, cause, site or severity before settling on B00.9.
Within B00, choose B00.9 (Herpesviral infection, unspecified) only when documentation doesn't support a more specific option: eczema herpeticum (B00.0), herpesviral vesicular dermatitis (B00.1), herpesviral gingivostomatitis and pharyngotonsillitis (B00.2), herpesviral meningitis (B00.3), herpesviral encephalitis (B00.4), herpesviral ocular disease (B00.5), disseminated herpesviral disease (B00.7) and other forms of herpesviral infections (B00.8).
It is not a CC or MCC, so as a secondary diagnosis it doesn't change the MS-DRG severity level.
In MS-DRG v44.0, it is part of the grouping logic for DRG 606 (Minor Skin Disorders with MCC, relative weight 1.5728), DRG 607 (Minor Skin Disorders without MCC, relative weight 0.8772), DRG 974 (HIV with Major Related Condition with MCC, relative weight 3.0506), DRG 975 (HIV with Major Related Condition with CC, relative weight 1.3252) and DRG 976 (HIV with Major Related Condition without CC/MCC, relative weight 0.8124), in MDC 09 (Diseases and Disorders of the Skin, Subcutaneous Tissue and Breast) and MDC 25 (Human Immunodeficiency Virus Infections), as a principal or secondary diagnosis. The DRG a claim lands in depends on the principal diagnosis, procedures and any CC/MCC secondary diagnoses.
More specific simplex herpes codes (official index)
- complicated NEC B00.89 — Other herpesviral infection
- congenital P35.2 — Congenital herpesviral [herpes simplex] infection
- conjunctivitis B00.53 — Herpesviral conjunctivitis
- external ear B00.1 — Herpesviral vesicular dermatitis
- eyelid B00.59 — Other herpesviral disease of eye
- hepatitis B00.81 — Herpesviral hepatitis
- keratitis (interstitial) B00.52 — Herpesviral keratitis
- myelitis B00.82 — Herpes simplex myelitis
- specified complication NEC B00.89 — Other herpesviral infection
- visceral B00.89 — Other herpesviral infection
Common questions about simplex herpes ICD-10 codes
What is the ICD-10 code for simplex herpes?
- B00.9 — Herpesviral infection, unspecified. More specific codes apply when the documentation supports them: B00.89, P35.2, B00.53, B00.1 and others below.
What is the ICD-10 code for complicated nec simplex herpes?
- B00.89 — Other herpesviral infection.
What is the ICD-10 code for congenital simplex herpes?
- P35.2 — Congenital herpesviral [herpes simplex] infection.
What is the ICD-10 code for conjunctivitis simplex herpes?
- B00.53 — Herpesviral conjunctivitis.
What is the ICD-10 code for external ear simplex herpes?
- B00.1 — Herpesviral vesicular dermatitis.
What is the ICD-10 code for eyelid simplex herpes?
- B00.59 — Other herpesviral disease of eye.
What is the ICD-10 code for hepatitis simplex herpes?
- B00.81 — Herpesviral hepatitis.
Is B00.9 billable?
- Yes. B00.9 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).
Can B00.9 be used as a principal diagnosis?
- Yes. The Medicare Code Editor doesn't restrict B00.9 as a principal diagnosis.
Is B00.9 a CC or MCC?
- No. B00.9 is neither a CC nor an MCC under MS-DRG v44.0.