ICD-10-CM 2027
ICD-10 code for spleen degeneration
From the official ICD-10-CM alphabetic index entry “Degeneration, degenerative › spleen”. Page updated September 29, 2026.
About coding spleen degeneration
The ICD-10-CM code for spleen degeneration is D73.0 (Hyposplenism). The official index lists 1 more specific code, so check the documentation for details such as type, cause, site or severity before settling on D73.0.
Within D73 (diseases of spleen), D73.0 is specifically for Hyposplenism. Related codes cover Hypersplenism (D73.1), chronic congestive splenomegaly (D73.2), abscess of spleen (D73.3), cyst of spleen (D73.4), infarction of spleen (D73.5), other diseases of spleen (D73.8) and disease of spleen, unspecified (D73.9).
Don't report D73.0 together with the conditions in its Excludes1 note: asplenia (congenital) (Q89.01) and postsurgical absence of spleen (Z90.81).
It is not a CC or MCC, so as a secondary diagnosis it doesn't change the MS-DRG severity level.
More specific spleen degeneration codes (official index)
- amyloid E85.4 — Organ-limited amyloidosis
Don't confuse with (Excludes1 for D73.0)
Common questions about spleen degeneration ICD-10 codes
What is the ICD-10 code for spleen degeneration?
- D73.0 — Hyposplenism. More specific codes apply when the documentation supports them: E85.4.
What is the ICD-10 code for amyloid spleen degeneration?
- E85.4 — Organ-limited amyloidosis.
Is D73.0 billable?
- Yes. D73.0 is a billable/specific ICD-10-CM code valid for FY2027 (October 1, 2026 – September 30, 2027).
Can D73.0 be used as a principal diagnosis?
- Yes. The Medicare Code Editor doesn't restrict D73.0 as a principal diagnosis.
Is D73.0 a CC or MCC?
- No. D73.0 is neither a CC nor an MCC under MS-DRG v44.0.